Arecoline hydrobromide Mai yuwuwar warkewa a cikin tsarin juyayi na tsakiya

Farashin Magana: USD15-20/g

Sunan samfur Arecoline
CAS No. 300-08-3
MF Saukewa: C8H14BrNO2
MW 236.109
EINECS 206-087-3
Adadin acidity (pka) 6.84 (a 25 ℃)
Wurin narkewa 171-175 ° C

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Arecoline, babban alkaloid mai aiki da ake samu a cikin areca goro, ya sami kulawa don yuwuwar warkewarsa wajen magance cututtukan hauka da rage cututtukan ciki. Wannan labarin yana nufin samar da taƙaitaccen tsari na tsarin aikin arecoline a cikin tsarin jiki daban-daban, ciki har da cavity na baka, tsarin juyayi na tsakiya, tsarin zuciya da jijiyoyin jini, da tsarin narkewa. Bugu da ƙari, za a bincika ayyukan kiwon lafiya da kuma tasirin guba na arecoline. A ƙarshe, za a tattauna aikace-aikacen arecoline a cikin abubuwan abinci na lafiya, magunguna, da shirye-shiryen kwaskwarima.

Arecoline, a nicotinic acid-tushen m parasympatomimetic stimulant alkaloid, da farko yana aiki azaman agonist na muscarinic acetylcholine receptors. Yana nuna tasirin parasympathetic maimakon radadin masu karɓar nicotinic acetylcholine kamar nicotine. Arecoline kuma yana hana AMPK (adenosine monophosphate-activated protein kinase) ta hanyar samar da nau'in oxygen mai amsawa (ROS) a cikin nau'ikan tantanin halitta daban-daban.

Tasirin Tsarin Jiki Daban-daban:

Tsarin Jijiya: Arecoline yana haɓaka tashin hankali, haɓaka koyo da ƙwaƙwalwa, kuma yana rage alamun damuwa da schizophrenia. Hakanan yana iya juyar da asarar ƙwaƙwalwar ajiya wanda scopolamine ya jawo.

Tsarin zuciya na zuciya: Arecoline yana aiki a matsayin vasodilator, yana ƙaruwa plasma nitric oxide, eNos, da mRNA magana, kuma yana nuna anti-thrombosis da anti-atherogenic effects. Hakanan yana rage IL-8 da sauran abubuwan.

Tsarin Endocrine: Arecoline yana ƙarfafa ƙwayoyin Leydig, yana haifar da haɓaka matakan testosterone. Yana kunna axis hypothalamic-pituitary-adrenal (HPA), yana haɓaka sakin hormone corticotropin (CRH). Bugu da ƙari, yana taimakawa hana tabarbarewar ƙwayoyin beta na pancreatic wanda ya haifar da yawan cin fructose.

Tsarin narkewa: Arecoline yana motsa tsarin narkewa ta hanyar kunna masu karɓar muscarinic. Yana ƙara ƙanƙancewar tsoka mai santsi na ciki da ɗigon tsoka na duodenum, ileum, da hanji.

Ayyukan Lafiya da Aikace-aikace:

Analgesia da Tsarin Jijiya ta Tsakiya: Arecoline hydrobromide yana nuna alamun analgesic kuma yana da tasiri mai tasiri akan tsarin kulawa na tsakiya.

Kiwon Lafiyar fata: Arecoline hydrobromide yana haɓaka metabolism na fata kuma yana nuna yuwuwar magance cututtukan fata da sauran cututtukan fata.

Detoxification da Diuretic Effects: Arecoline hydrobromide share zafi, detoxifies, kawar da dampness da kumburi, kuma yana da diuretic Properties.

Antibacterial da Dissolving Duwatsu: Arecoline hydrobromide yana nuna kaddarorin antibacterial da ikon narkar da duwatsu.

Ƙarfafa Jini da Jini: Arecoline hydrobromide yana taimakawa ƙarfafa tasoshin jini da inganta yaduwar jini.

Aikace-aikace:

Ƙarin Abinci na Lafiya: Ana iya amfani da Arecoline azaman sinadari a cikin abubuwan abinci na lafiya waɗanda ke niyya takamaiman ayyukan kiwon lafiya, kamar haɓaka fahimi ko lafiyar fata.

Pharmaceuticals: Arecoline na iya samun yuwuwar aikace-aikace a cikin magunguna, musamman a cikin maganin cututtukan hauka ko azaman maganin antihelmintic.

Shirye-shiryen kwaskwarima: Inganta metabolism na fata na Arecoline da yuwuwar kaddarorin warkar da raunuka sun sa ya zama ɗan takara don shirye-shiryen kwaskwarima, musamman waɗanda ke yin niyya ga cututtukan fata ko wasu cututtukan da ke da alaƙa da fata.

Arecoline, mai aiki alkaloid samu a cikin areca goro, nuna daban-daban warkewa effects da kuma yana da aikace-aikace a daban-daban tsarin jiki. Hanyoyin aikin sa ana yin sulhu da farko ta hanyar masu karɓar muscarin kuma suna nuna tasirin parasympathetic. Yayin da arecoline ya nuna alƙawarin magance wasu yanayi na kiwon lafiya, yana da mahimmanci a yi la'akari da yiwuwar tasiri mai guba da kuma abubuwan da ke tattare da ciwon daji da ke hade da amfani da shi. Tuntuɓi mu idan akwai bukata.

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