0102030405
Vincristine Sulfate Foda Vincristine Tsabtace Vincristine CAS 57-22-7
Cikakken Bayani
Vincristine fari ne zuwa kashe-fari crystalline foda.It ne kusan insoluble a cikin ruwa, amma shi narke a cikin wasu Organic kaushi.The tsarki fili ne wari da yawanci adana a bushe, duhu wuri karkashin sarrafawa yanayin zafi don kula da kwanciyar hankali. It is a naturally occurring alkaloid derived from the Madagascar periwinkle plant(Catharanthus roseus) .Its chemical structure resembles that of vinblastine,wani vinca alkaloid.Vincristine ne yadu amfani da magani na daban-daban na ciwon daji,ciki har da cutar sankarar bargo,lymphoma,da kuma m ciwace-ciwacen daji. .
Vincristine shine mai hana microtubule wanda ke rushe samuwar microtubules, waɗanda sune mahimman abubuwan da ke cikin cytoskeleton tantanin halitta. vincristine musamman tasiri a kan hanzari rarraba ciwon daji Kwayoyin.Clinical aikace-aikace na vincristine hada da magani na daban-daban malignancies irin su m lymphoblastic cutar sankarar bargo (ALL), Hodgkin ta da kuma wadanda ba Hodgkin ta lymphomas, yara da manya m ciwace-ciwacen daji, neuroblastoma, da rhabdomyosarcoma.Vinstine ne sau da yawa amfani da Cristine. a hade tare da wasu magungunan chemotherapeutic a matsayin wani ɓangare na tsarin kulawa da magunguna masu yawa, wanda aka sani da haɗin gwiwar chemotherapy.
Bugu da ƙari ga amfani da shi na farko a maganin ciwon daji, vincristine ya kuma nuna tasiri a cikin kula da wasu yanayi marasa lafiya. Ana amfani da shi a cikin maganin idiopathic thrombocytopenic purpura (ITP), rashin lafiya na autoimmune wanda ke da ƙananan adadin platelet. Bugu da ƙari kuma. , vincristine ya nuna yuwuwar a cikin kula da yanayin yanayi daban-daban, ciki har da na kullum kumburi demyelinating polyneuropathy (CIDP) da kuma pediatric autoimmune neuropsychiatric cuta hade da streptococcal cututtuka (PANDAS).
Bugu da ƙari kuma, vincristine's anti-angiogenic Properties sun haifar da bincike na yiwuwar amfani da shi a cikin maganin cututtuka daban-daban, ciki har da ciwon sukari retinopathy da shekaru masu alaka da macular degeneration. A taƙaice, vincristine, wanda aka samo daga tsiron periwinkle na Madagascar, wakili ne mai mahimmanci na rigakafin ciwon daji wanda ke rushe ƙwayoyin microtubule kuma yana haifar da mutuwar tantanin halitta a rarraba sel. aikace-aikace masu yawa na asibiti sun haɗa da maganin cutar sankarar bargo, lymphoma, ciwace-ciwacen ciwace-ciwacen ƙwayoyi, da wasu yanayi marasa lafiya. Yayin da ake amfani da shi na farko a cikin maganin ciwon daji, bincike na ci gaba yana ci gaba da gano yiwuwarsa a cikin yanayin kiwon lafiya daban-daban.
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