0102030405
Cetrorelix: He Antagonist GnRH no ka hoʻoulu ʻana i ka ovarian a me nā maʻi Hormone-Sensitive.
Ka wehewehe kikoʻī
ʻO Cetrorelix, i ʻike ʻia ʻo cetrorelix acetate a kūʻai ʻia ma lalo o ka inoa inoa ʻo Cetrotide, he antagonist gonadotropin-releasing hormone (GnRH) injectable. Hoʻohana nui ʻia kēia decapeptide synthetic i ka hana hou ʻana e kāohi i ka piʻi ʻana o ka hormone luteinizing (LH) premature, hiki ke hoʻopau i ka manawa o ka ovulation. Hoʻohui ʻia, loaʻa i ka cetrorelix nā noi i ka mālama ʻana i nā maʻi maʻi maʻi hormone-sensitive a me kekahi mau maʻi gynecological benign. ʻO kāna hana e pili ana i ka pale ʻana i ka hana a GnRH ma ka pituitary gland, e alakaʻi ana i ka hoʻopau wikiwiki ʻana i ka LH a me ka follicle-stimulating hormone (FSH) hana a me ka hana.
I loko o ka pōʻaiapili o ka hoʻoulu hou ʻana, hoʻohana ʻia ka cetrorelix ma ke ʻano he injection i kēlā me kēia lā i ka wā i hoʻomaka ai ka hoʻoulu ʻana o ka follicle a ke kokoke mai nei nā hōʻike o ka oʻo ʻana o ka follicle. ʻO kāna kumu nui, ʻo ia ka pale ʻana i ka piʻi ʻana o ka LH endogenous e hoʻoulu i ka ovulation untimely ma mua o ka hoʻolālā ʻana o ke kanaka chorionic gonadotropin (hCG) e ke kauka lapaʻau. Ma ke kāohi ʻana i ka ovulation premature, kōkua ka cetrorelix i ka mālama ʻana i nā kūlana maikaʻi loa no ka hōʻiliʻili hua manu a me ka mālama ʻana i ka ʻenehana hānau hou. He mea ʻokoʻa ia i nā agonists GnRH, e koi ana i kahi hoʻomaka mua e lanakila ai i kā lākou hopena agonistic.
ʻO kahi pōmaikaʻi koʻikoʻi o ka cetrorelix ʻo ia ka pili ʻana me ka follitropin alpha, no ka mea hiki ke hui pū ʻia nā lāʻau ʻelua me ka ʻole o ka hoʻololi ʻana i ko lākou palekana a me ka pono. Hoʻonui kēia ʻoluʻolu i ka ʻike lapaʻau holoʻokoʻa no nā poʻe maʻi e mālama ana i ka hoʻoulu ʻana i ka ovarian. Hiki ke hoʻohana ʻia no ka mālama ʻana i kekahi mau maʻi gynecological maikaʻi, me ka endometriosis, fibroids uterine, a me ka thinning endometrial. Ma ka pale ʻana iā GnRH, hoʻopau ka cetrorelix i ka cascade hōʻailona e hoʻoulu ai i ka hana hormone i kēia mau kūlana, e hāʻawi ana i nā pono therapeutic.
Hāʻawi ʻo Cetrorelix i nā pono he nui i kāna noi lapaʻau. He wikiwiki a hoʻohuli ʻia, hāʻawi i ka mana pololei i ka manawa ovulation. ʻO kona hoʻohana ʻana i kahi papahana hoʻoulu ʻana i ka ovarian e pili kokoke ana i kahi papahana hoʻomalu ovulation physiological, e hoʻolike ana i ka pōʻai kūlohelohe. Eia kekahi, hoʻemi ka cetrorelix i ka nui o nā gonadotropins (Gn) i koi ʻia, a i kekahi mau manawa, hiki ke hoʻohana ʻia nā agonists GnRH ma kahi o ka hCG e hoʻoulu ai i ka ovulation, e hōʻemi ana i ka hanana o ka ovarian hyperstimulation syndrome (OHSS).
He kuleana koʻikoʻi ʻo Cetrorelix, he antagonist GnRH, i ka hoʻoulu ʻana o ka ovarian no ke kōkua ʻana i ka hana hou ʻana, ka pale ʻana i ka ovulation premature a me ka maikaʻi o ka manawa o ka ʻohi hua manu. ʻO kona kūlike me ka follitropin alpha e hoʻonui i ka maʻalahi no nā maʻi. Hōʻike pū ʻo Cetrorelix i ka maikaʻi i ka mālama ʻana i nā maʻi maʻi maʻi hormone-sensitive a me kekahi mau maʻi gynecological benign, e hāʻawi ana i nā pono therapeutic i kēia mau kūlana. Me kona mau hana wikiwiki a hoʻololi hou, pili kokoke i ka mana physiological, hoʻohana ākea, palekana kiʻekiʻe, a me ka hoʻokō maikaʻi ʻana, he lāʻau koʻikoʻi ka cetrorelix i ka lāʻau lapaʻau hānau a ma waho.
Hōʻike
