ʻO Triptorelin, kahi decapeptide synthetic a me ka analog o ka hormone hoʻokuʻu gonadotropin-releasing hormone (GnRH), ua loaʻa ka ʻike nui i ka ʻoihana lapaʻau. Hoʻohana ʻia ia no nā hōʻailona like ʻole, me ka mālama ʻana i ka endometriosis, fibroids, prostate cancer, precocious puberty, a me ka infertility. Hana ʻo Triptorelin ma ka hoʻoulu mua ʻana i ka huna ʻana o nā gonadotropins a ma hope iho e hoʻohaʻahaʻa i ka gonadotropin-releasing hormone receptors, e hopena i ka hoʻemi lōʻihi o ka hoʻokuʻu ʻana o ka gonadotropin.
Hōʻike ʻo Triptorelin i kahi ākea o nā hopena therapeutic. I nā wahine, hoʻohana ʻia e mālama i ka endometriosis, fibroids uterine, a me ka infertility. ʻO ka hoʻomau mau ʻana o Triptorelin e kāohi pono i ka hana ʻana o ka estradiol, e alakaʻi ana i ka hoʻopau ʻana i ka ʻiʻo endometrial ectopic i ka endometriosis. Eia hou, ua hōʻike nā haʻawina i ka emi nui o ka nui o nā fibroids uterine, me ka hapa nui o nā maʻi e loaʻa ana i ka amenorrhea ma hope o ka malama mua o ka mālama ʻana. No ka infertility, triptorelin inhibits the secretion of gonadotropins, hoʻomaikaʻi i ka maikaʻi o ka follicle production a me ka hoʻonui ʻana i ka nui o nā follicles, ma laila e hoʻonui ai i ka manawa o nā ʻano hana hoʻohua i kōkua ʻia e like me in vitro fertilization.
I nā kāne, hoʻohana pinepine ʻia ka triptorelin no ka mālama ʻana i ka maʻi prostate. Hana ia ma ka hoʻonui mua ʻana i ke koko luteinizing hormone (LH) a me ka follicle-stimulating hormone (FSH), a ukali ʻia e ka emi ʻana o kēia mau hormones a me ka emi ʻana o nā pae testosterone koko. ʻO kēia hoʻemi ʻana i nā pae testosterone e kōkua i ka mālama ʻana i ka maʻi prostate a me kāna mau hōʻailona pili. Ua maikaʻi nō hoʻi nā injections Triptorelin i ka mālama ʻana i ka wā ʻōpio precocious, kaohi ʻana i ka hypersecretion pituitary o nā gonadotropins a me ka hoʻomaʻamaʻa ʻana i nā pae hormone.
ʻO nā hana o ka triptorelin e pili ana i ka hoʻopaʻa ʻana i ka huna ʻana o ka gonadotropin a me ka pale ʻana i ka gonadotropic ma o ka desensitizing peripheral GnRH receptors. Ua hōʻike nā haʻawina holoholona a me nā kānaka i nā hopena pale o ka hoʻohana mau ʻana i ka triptorelin ma ka huna ʻana o ka gonadotropin, e alakaʻi ana i ka hoʻopau ʻana i ka hana testicular a me ovarian. Hōʻike hou ʻia ka maikaʻi o Triptorelin e ka hoʻomaikaʻi ʻana i nā hōʻailona e like me ka dysmenorrhea, ka ʻeha pelvic mau loa, a me ka ʻeha i ka wā o ka moekolohe.
Hāʻawi mākou i nā ʻano hoʻonā i hoʻoponopono ʻia no ʻoe e koho mai
Triptorelin injection: 0.1 mg/1 ml.
Triptorelin hoʻokuʻu i hoʻonui ʻia: 3.75 mg; 11.25 mg; 22.5 mg.
ʻO Triptorelin pamoate no ka inikua: 15 mg i kēlā me kēia ʻōmole (loaʻa 1 ʻōmole o 2 ml solvent). Inā loaʻa iā ʻoe nā pono ʻē aʻe, hiki iā ʻoe ke hoʻokaʻaʻike mai iā mākou a hāʻawi mākou iā ʻoe i nā lawelawe hana maʻamau a pololei.
Ma ke ʻano he analog gonadotropin ikaika, hāʻawi ʻo Triptorelin i kahi ʻano o nā noi therapeutic no nā kāne a me nā wahine. ʻO kona hiki ke hoʻoponopono i nā kiʻekiʻe o ka hormone a kāohi i ka huna ʻana o ka gonadotropin ua hōʻoia maikaʻi i ka mālama ʻana i nā kūlana e like me endometriosis, fibroids uterine, prostate cancer, precocious puberty, and infertility. Me ka maikaʻi o ka lāʻau lapaʻau a me ka versatility, hoʻomau ka triptorelin i ka hāʻawi nui ʻana i ke kahua o ka lāʻau lapaʻau hānau a me ka oncology.
