Abarelix Hwj chim Gonadotropin-Tshuaj Hormone Antagonist rau Kev Kho Mob Cancer Prostate
Cov lus piav qhia ntxaws
Abarelix, ib qho hluavtaws decapeptide, nthuav tawm muaj zog antagonistic ua haujlwm tawm tsam ntuj gonadotropin-tso tshuaj hormone (GnRH). Nws yog feem ntau siv los kho cov neeg mob uas muaj cov tsos mob ntawm tus mob qog nqaij hlav prostate uas tsis tsim nyog rau luteinizing hormone-tso cov tshuaj hormone agonists lossis phais castration. Los ntawm ncaj qha inhibiting lub secretion ntawm luteinizing hormone (LH) thiab follicle-stimulating hormone (FSH), abarelix zoo txo cov zus tau tej cov testosterone los ntawm cov noob qes. cia peb tshawb txog cov kev qhia kho mob, cov txheej txheem ntawm kev ua, thiab kev siv ntawm abarelix.
Abarelix tau qhia rau kev kho mob palliative ntawm cov neeg mob uas muaj mob qog noj ntshav prostate uas ua tau raws li cov qauv tshwj xeeb. Nws raug pom zoo rau cov neeg mob uas tsis tsim nyog cov neeg sib tw rau luteinizing hormone-tso cov tshuaj hormone agonists, tsis kam phais castration, thiab muaj kev pheej hmoo ntxiv xws li lub peev xwm rau kev puas hlwb puas tsuaj vim metastasis, ureteral lossis zais zis orifice cuam tshuam los ntawm kev yaig hauv zos lossis metastasis, los yog mob metastatic pob txha loj heev uas yuav tsum tau siv cov tshuaj narcotic tas mus li.
Raws li kev txhaj tshuaj gonadotropin-tso tshuaj hormone antagonist (GnRH antagonist), abarelix plays lub luag haujlwm tseem ceeb hauv kev txo qis kev tsim cov testosterone hauv cov neeg mob uas muaj cov tsos mob ntawm prostate cancer thaum lwm txoj kev kho mob tsawg. Nws ncaj qha inhibits qhov tso tawm ntawm LH thiab FSH, uas tom qab txo qis kev tso tawm ntawm testosterone los ntawm cov noob qes. Los ntawm depriving prostate cancer hlwb ntawm testosterone, abarelix pab tswj tus kab mob thiab alleviation ntawm cov tsos mob.
Kev siv ntawm abarelix hauv kev kho mob qog noj ntshav prostate muab ib qho txiaj ntsig zoo rau cov neeg mob uas tsis tuaj yeem hla lossis tsis kam phais castration lossis lwm yam tshuaj hormonal. Nws lub peev xwm los tiv thaiv GnRH thiab txo qis testosterone ntau lawm muaj kev pab cuam palliative thiab pab tswj kev kis tus kab mob. Los ntawm kev txo cov qib testosterone, abarelix pab hauv inhibiting kev loj hlob thiab kev loj hlob ntawm cov qog nqaij hlav qog nqaij hlav prostate, yog li muab cov tsos mob zoo thiab txhim kho tus neeg mob lub neej zoo.
Abarelix, lub zog gonadotropin-tso cov tshuaj hormone antagonist, yog ib qho kev xaiv zoo rau cov neeg mob uas muaj cov tsos mob ntawm prostate cancer uas tsis tsim nyog rau luteinizing hormone-tso hormone agonists lossis phais castration. Los ntawm ncaj qha inhibiting LH thiab FSH secretion, abarelix zoo txo qis testosterone ntau lawm, uas yog ib qho tseem ceeb rau kev loj hlob thiab kev loj hlob ntawm prostate cancer. Nws cov kev siv muab palliative nyem thiab pab tswj tus kab mob hauv cov neeg mob uas muaj kev xaiv kho mob tsawg. Abarelix, ua lag luam raws li Plenaxis, ua haujlwm tseem ceeb hauv kev tawm tsam kev mob qog noj ntshav prostate, pab txhawb kev txhim kho cov neeg mob thiab txhim kho lub neej zoo.
Nco ntsoov tiv tauj peb yog tias xav tau.
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