CARBETOCIN Postpartum Hemorrhage hmoov
Cov lus piav qhia ntxaws
Taw qhia:
Carbetocin, ib qho hluavtaws ua haujlwm ntev oxytocin analog, nthuav tawm cov khoom zoo ib yam li oxytocin tshwm sim. Nws ua raws li ib tug agonist, khi rau uterine smooth nqaij receptors thiab ua rau lub uterine contractions. Carbetocin feem ntau ua haujlwm zoo hauv cev xeeb tub thiab yug menyuam tshiab, vim tias cov ntsiab lus oxytocin receptor muaj ntau dua thaum lub sijhawm no. Nyob rau hauv tsab ntawv no, peb yuav tshawb xyuas cov chaw kho mob thiab chaw muag tshuaj ntawm carbetocin, tsom rau nws txoj kev siv hauv kev tswj cov ntshav tom qab yug me nyuam thiab tiv thaiv uterine contraction tom qab phais tas.
Postpartum Hemorrhage Control:
Carbetocin yog ib qho tshuaj muaj txiaj ntsig siv los tswj ntshav qab zib, uas yog hais txog ntshav ntau dhau tom qab yug menyuam. Los ntawm inducing uterine contractions, carbetocin pab restore uterine tone, txo txoj kev pheej hmoo ntawm los ntshav ntau. Nws cov txiaj ntsig yog nyob rau hauv nws lub peev xwm los ua kom qhov zaus thiab qhov nro ntawm lub tsev menyuam, tiv thaiv lossis txo qis ntshav tom qab yug menyuam.
Carbetocin feem ntau yog siv tom qab xaiv cov tshuaj loog epidural lossis txha caj qaum thaum cov txheej txheem phais phais kom tiv thaiv uterine contraction thiab tom qab yug me nyuam los ntshav. Qhov kev xyaum no ua kom ntseeg tau tias cov leeg ntawm lub tsev menyuam tseem raug cog lus, txo qhov kev pheej hmoo los ntshav ntau dhau. Txawm li cas los xij, kev siv carbetocin nyob rau hauv cov chaw kho mob xwm txheej ceev, cov kab mob hauv tsev kho mob classic, thiab nyob rau hauv lwm hom tshuaj loog lossis nyob rau hauv muaj cov mob tshwj xeeb tsis tau kawm ntau. Yog li ntawd, yuav tsum tau ceev faj thaum xav txog kev tswj hwm carbetocin hauv cov xwm txheej no.
Mechanism ntawm Action:
Carbetocin ua haujlwm raws li oxytocic, antihemorrhagic, thiab uterotonic tshuaj, feem ntau tsom rau lub paj hlwb peripheral. Nws ua raws li agonist ntawm peripheral oxytocin receptors, tshwj xeeb tshaj yog nyob rau hauv myometrium (uterine leeg). Cov oxytocin receptors no yog G protein-coupled, thiab lawv qhov kev ua kom muaj cov tub txib thib ob thiab tsim cov inositol phosphates. Carbetocin ua raws li cov txheej txheem no, khi tsis tau xaiv ntawm cov khoom siv sab nraud N-terminus thiab voj E2 thiab E3 ntawm oxytocin receptor. Txawm hais tias carbetocin thiab oxytocin muaj kev sib raug zoo zoo sib xws rau cov receptors, carbetocin's biological nyhuv yog kwv yees li 50% ntawm endogenous lossis exogenous oxytocin. Qhov tseem ceeb, carbetocin muaj cov nyhuv ntev dua li oxytocin, tsuas yog xav tau ib koob nkaus xwb. Nws kuj inhibits kev tso tawm ntawm endogenous oxytocin, cuam tshuam lub uterine tswv yim voj nrog lub hypothalamus thiab txo ob lub hauv paus thiab peripheral oxytocin tso. Carbetocin tuaj yeem suav hais tias yog ib tus neeg tsis ncaj ncees agonist ntawm oxytocin receptor.
Thaum cev xeeb tub, cov synthesis ntawm oxytocin receptors nyob rau hauv lub tsev menyuam tau nce, nce mus txog nws lub ncov thaum lub sij hawm cev xeeb tub thiab yug menyuam. Yog li ntawd, kev tswj hwm ntawm carbetocin los yog lwm yam oxytocin analogs thaum lub sij hawm los yog tom qab yug me nyuam yuav txhim kho uterotonic thiab contractile cov teebmeem. Txawm li cas los xij, carbetocin tsis muaj kev cuam tshuam rau cov poj niam cev xeeb tub uas tsis muaj oxytocin receptor qhia. Tsis tas li ntawd, carbetocin pab txhawb cov ntshav thickening, ntxiv txo qhov kev pheej hmoo ntawm ntshav qab zib.
Kev ceev faj thiab kev txwv:
Nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias carbetocin yuav tsum tsis txhob siv rau kev ua haujlwm induction lossis augmentation, vim nws tuaj yeem ua rau mob plawv lossis ua pa nyuaj rau niam thiab menyuam mos.
Xaus:
Carbetocin, ib qho hluavtaws oxytocin analog, muab txoj hauv kev zoo rau kev tswj cov ntshav tom qab yug menyuam thiab tiv thaiv los ntshav ntau dhau tom qab phais tas. Los ntawm kev ua raws li cov txheej txheem ntawm oxytocin tshwm sim, carbetocin induces uterine contractions thiab txhawb uterine tone. Txawm li cas los xij, nws yuav tsum tau ua tib zoo xav txog cov xwm txheej tshwj xeeb, thiab cov kws kho mob yuav tsum tau ceev faj thaum siv cov carbetocin.
Nco ntsoov tiv tauj peb rau Carbetocin Factory direct supply price.
Specification
