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0102 ib0304 ib05
Flumazenil A Selective GABAA Receptor Antagonist thiab nws cov kev siv kho mob
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Flumazenil A Selective GABAA Receptor Antagonist thiab nws cov kev siv kho mob

Flumazenil A Selective GABAA Receptor Antagonist thiab nws cov kev siv kho mob

Nqe: USD 1-2 / g

  • Khoom npe Flumazenil
  • CAS Nr. 78755-81-4
  • MF C15H14FN3O3
  • MW 303.288363 ib
  • EINECS 616-650-9
  • Qhov ntom 1.39 ib
  • Melting point 201-203 ℃
Tiv tauj peb
cov khoom paub meej

Cov lus piav qhia ntxaws

Flumazenil, tseem hu ua flumazepil lossis lub npe npe Ro 15-1788, yog ib qho kev xaiv GABAA receptor antagonist uas tuaj yeem siv los ntawm kev txhaj tshuaj, otic insertion, lossis intranasally. Nws ua raws li ob qho tib si antagonist thiab tshuaj tua kab mob rau benzodiazepines, tshwj xeeb tshaj yog thaum noj ntau dhau, los ntawm kev sib tw inhibition. Kab lus no tshawb txog cov txiaj ntsig kho mob, kev siv tshuaj tua kab mob, thiab kev siv cov tshuaj flumazenil hauv ntau qhov chaw kho mob.

I. Mechanism of Action:
A. Xaiv GABAA receptor antagonist
B. Competitive inhibition ntawm qhov chaw paub txog benzodiazepine
C. Reversal ntawm cov teebmeem benzodiazepine

II. Antidote rau Benzodiazepine Overdose:
A. Qhov tseem ceeb ntawm kev sib tw inhibition nyob rau hauv cov ntaub ntawv overdose
B. Cov txiaj ntsig ntawm flumazenil hauv kev thim rov qab sedation ntau dhau
C. Cov teeb meem thiab kev pheej hmoo cuam tshuam nrog kev siv kho mob hnyav
D. Kev txiav txim siab ntau npaum li cas thiab ua tib zoo saib xyuas

17163636651623 ZPO

III. Daim ntawv thov tom qab phais:

A. Reversal ntawm sedative teebmeem ntawm benzodiazepines tom qab phais

B. Zoo sib xws rau kev siv naloxone hauv opioid reversal

C. Kev tshuaj xyuas tshuaj loog thiab tshuaj xyuas tom qab kev phais


IV. Kev kho mob ntawm Non-Benzodiazepine Hypnotic Overdose:

A. Cov txiaj ntsig ntawm flumazenil hauv kev kho zolpidem, zaleplon, thiab zopiclone overdoses


V. Muaj peev xwm siv tau hauv Hypersomnia thiab Gastrointestinal Side Effects:

A. Kev txo qis ntawm kev tsaug zog ntau thaum nruab hnub hauv thawj hypersomnias

B. Kev txo qis ntawm kev mob plab hnyuv los ntawm kev kho mob qog noj ntshav

C. Kev tiv thaiv cov kab mob hauv plab hnyuv thaum siv tshuaj kho mob thiab kho hluav taws xob


VI. Qhov tseem ceeb ntawm Balancing GABAA Receptor Inhibition:

A. Tiv thaiv cov kab mob hauv plab los ntawm DNA puas thaum lub sij hawm siv hluav taws xob

B. Xyuas kom tsis txhob muaj kab mob qog noj ntshav



1716363224318 wf


Flumazenil, ib qho kev xaiv GABAA receptor antagonist, ua hauj lwm pab raws li ib tug tseem ceeb tshuaj tiv thaiv nyob rau hauv benzodiazepine overdose mob, muab kev sib tw inhibition thiab reversal ntawm sedative teebmeem. Nws cov ntawv thov txuas ntxiv mus rau kev siv tom qab phais, kev kho mob ntawm cov tshuaj uas tsis yog benzodiazepine hypnotic overdoses, thiab cov txiaj ntsig zoo hauv hypersomnia thiab kev mob plab hnyuv. Ua tib zoo saib xyuas thiab saib xyuas cov kev pheej hmoo yog qhov tseem ceeb thaum siv tshuaj flumazenil, tshwj xeeb tshaj yog nyob rau hauv kev saib xyuas mob hnyav thiab tom qab kev phais. Kev tshawb fawb ntxiv yog xav tau los tshawb nrhiav nws lub peev xwm tag nrho hauv kev tiv thaiv cov kab mob hauv plab hnyuv thaum kho mob qog noj ntshav thaum tswj kev mob qog noj ntshav-tua tau zoo.

Specification

1716359370385 ib