Rosuvastatin antilipemic tus neeg sawv cev Rosuvastatin kho dyslipidemia

Rosuvastatin inhibits cov enzyme hydroxymethylglutaryl-CoA reductase hauv daim siab, uas txo cov roj cholesterol synthesis thiab txo cov roj cholesterol thiab triglycerides. Tsis tas li ntawd, Rosuvastatin ua rau kom lub siab nce siab thiab rhuav tshem cov roj lipoprotein tsawg (LDL-C), thaum tseem nce qib siab lipoprotein cholesterol (HDL-C). Ntxiv nrog rau nws cov lipid-txo cov teebmeem, Rosuvastatin tau pom tias muaj cov tshuaj tiv thaiv atherosclerotic, tiv thaiv inflammatory, antioxidant, plaque stabilizing, thiab txhim kho endothelial muaj nuj nqi.

Rosuvastatin yog tsim los ntawm fermentation ntawm Aspergillus terreus los yog los ntawm cov tshuaj synthesis. Thaum noj, nws feem ntau metabolized nyob rau hauv daim siab thiab hloov mus rau hauv ntau yam metabolites, nrog rau cov nquag metabolites uas inhibit HMG-CoA reductase. Cov tshuaj thiab nws cov metabolites feem ntau yog tawm hauv cov quav, nrog me me tawm hauv cov zis.