Triptorelin, hluavtaws decapeptide thiab analog ntawm natural gonadotropin-tso hormone (GnRH), tau txais kev lees paub tseem ceeb hauv kev kho mob. Nws yog siv rau ntau yam indications, nrog rau kev kho mob ntawm endometriosis, fibroids, prostate cancer, precocious puberty, thiab infertility. Triptorelin ua los ntawm thawj zaug stimulating lub secretion ntawm gonadotropins thiab tom qab downregulating gonadotropin-tso cov tshuaj hormones receptors, ua rau lub sij hawm ntev ntawm gonadotropin tso tawm.
Triptorelin nthuav tawm ntau yam kev kho mob. Hauv cov poj niam, nws yog siv los tswj endometriosis, uterine fibroids, thiab infertility. Triptorelin txoj kev tswj hwm tas mus li muaj txiaj ntsig zoo inhibits kev tsim cov estradiol, ua rau muaj kev cuam tshuam ntawm ectopic endometrial cov ntaub so ntswg hauv endometriosis. Tsis tas li ntawd, cov kev tshawb fawb tau pom qhov txo qis ntawm qhov loj ntawm lub tsev menyuam fibroids, nrog rau cov neeg mob feem ntau ntsib amenorrhea tom qab thawj lub hlis ntawm kev kho mob. Rau kev xeeb tub, triptorelin inhibits qhov tso tawm ntawm gonadotropins, txhim kho qhov zoo ntawm cov follicle ntau lawm thiab nce cov follicles, yog li txhim kho txoj hauv kev muaj txiaj ntsig ntawm kev pabcuam kev loj hlob zoo li hauv vitro fertilization.
Hauv cov txiv neej, triptorelin feem ntau yog siv los tswj kev mob qog noj ntshav prostate. Nws ua los ntawm kev pib nce ntshav luteinizing hormone (LH) thiab follicle-stimulating hormone (FSH), tom qab los ntawm kev txo qis hauv cov tshuaj hormones thiab txo qis hauv cov ntshav testosterone theem. Qhov kev txo qis hauv testosterone qib pab kho mob qog noj ntshav prostate thiab nws cov tsos mob cuam tshuam. Kev txhaj tshuaj Triptorelin kuj tseem muaj txiaj ntsig zoo hauv kev kho mob ntawm precocious puberty, inhibiting pituitary hypersecretion ntawm gonadotropins thiab normalizing cov tshuaj hormones.
Cov txheej txheem ntawm kev ua ntawm triptorelin koom nrog ob qho tib si kev tawm tsam ntawm gonadotropin secretion thiab ncaj qha gonadotropic inhibition los ntawm desensitizing peripheral GnRH receptors. Tsiaj thiab tib neeg kev tshawb fawb tau pom tias inhibitory cuam tshuam ntawm kev siv triptorelin ntev ntawm gonadotropin secretion, ua rau muaj kev cuam tshuam ntawm cov qog nqaij hlav thiab zes qe menyuam. Triptorelin qhov kev ua tau zoo yog ua pov thawj ntxiv los ntawm kev kho mob hauv cov tsos mob xws li dysmenorrhea, mob plab pelvic, thiab mob thaum muaj kev sib deev.
Peb muab ntau yam kev daws teeb meem rau koj xaiv los ntawm
Triptorelin txhaj: 0.1 mg / 1 ml.
Triptorelin ncua-tso txhaj tshuaj: 3.75 mg; 11.25 mg; 22.5 mg yog '
Triptorelin pamoate rau kev txhaj tshuaj: 15 mg rau ib lub raj mis (muaj 1 lub raj mis ntawm 2 ml hnyav). Yog tias koj muaj lwm yam kev xav tau, koj tuaj yeem tiv tauj peb thiab peb yuav muab kev pabcuam rau koj tam sim thiab meej.
Raws li lub zog gonadotropin analogue, Triptorelin muaj ntau yam kev siv tshuaj kho mob rau cov txiv neej thiab poj niam. Nws muaj peev xwm tswj hwm cov tshuaj hormones thiab inhibit gonadotropin secretion tau ua pov thawj zoo hauv kev tswj cov mob xws li endometriosis, uterine fibroids, prostate cancer, precocious puberty, thiab infertility. Nrog nws cov kev ua tau zoo thiab kev siv ntau yam, triptorelin tseem ua rau muaj txiaj ntsig zoo rau thaj chaw ntawm cov tshuaj tua kab mob thiab oncology.Kev nkag siab txog cov txheej txheem ntawm kev txiav txim thiab muaj kev npaj ntawm triptorelin tso cai rau cov kws kho mob los kho cov phiaj xwm kho mob rau tus neeg mob xav tau.
