Nkọwa zuru ezu
Clomiphene, ọgwụ FDA kwadoro nke a na-ejikarị eme ihe maka nsogbu ọmụmụ nwanyị, ka a na-ewere na ọ dịghị mma maka ụmụ nwoke. Otú ọ dị, ndị na-arụ ọrụ nke ọma achọpụtala ihe nwere ike iji clomiphene mee ihe na ụmụ nwoke nwere ọnụ ọgụgụ spam dị ala nke ihe mkpụrụ ndụ ihe nketa ma ọ bụ steroid jiri. Na mgbakwunye, ndị na-ahụ maka ahụ nwoke amalitela iji clomiphene dị ka ọgwụ na-edozi testosterone iji kwalite mmepe akwara. Anyị na-enye nkọwapụta nke usoro omume nke clomiphene, mmetụta ya na ọkwa hormone, yana uru na ihe ize ndụ ọ nwere maka ụmụ nwoke.
A maara Clomiphene na-emetụta axis estrogen n'ime ahụ, ọ bụ ezie na usoro ya kpọmkwem na-anọgide na-adịtụ omimi. Ọ na-emekọrịta ihe na ndị na-anabata estrogen na anụ ahụ dị iche iche, gụnyere hypothalamus, pituitary gland, ovaries, endometrium, ikpu, cervix, adrenal glands, peripheral adipose tissue, imeju, na testes. N'ime ụmụ nwanyị, clomiphene na-arụ ọrụ na hypothalamus na pituitary gland, na-akpali mmepụta nke gonadotropin na-ahapụ hormone (GnRH), hormone na-akpali akpali (FSH), na hormone luteinizing (LH). Ihe mkpali a na-akwalite ovulation. N'ime ụmụ nwoke, clomiphene na-arụkwa ọrụ na hypothalamus na pituitary gland, na-eduga n'ịbawanye mmepụta nke testosterone na spam.
N'adịghị ka nkwenkwe ndị a ma ama, clomiphene adịghị ebelata ọkwa estrogen n'ime ahụ. N'ezie, ọ nwere ike ịkwalite secretion nke estrogen ruo n'ókè ụfọdụ na ụmụ nwoke. Ọ dị mkpa maka ndị mmadụ n'otu n'otu na-eji clomiphene, karịsịa ndị na-arụ ọrụ nwoke, iji nyochaa ma testosterone na estradiol ọkwa iji zere mmetụta ndị nwere ike ime dị ka gynecomastia (mmụba ara nwoke).
Ndị na-arụ ọrụ nwoke na nwanyị na-ejikarị clomiphene dị ka ihe mgbakwunye na usoro steroid ha. Otú ọ dị, ọ dị mkpa iburu n'obi na clomiphene adịghị ekewa dị ka ọgwụ na-emega ahụ na enweghi mmetụta androgenic. A na-ejikọta clomiphene ogologo oge na ụmụ nwoke na maromastia (akara ara) na ụbụrụ testicular, ọ bụ ezie na e guzobebeghị njikọ doro anya n'etiti clomiphene na mmetụta ndị a.
Ọ bụ ezie na ndị na-eme egwuregwu na ndị na-eme egwuregwu na-eji clomiphene na-amụbawanye, irè ya na ụmụ nwoke ka na-ejighị n'aka n'ihi ntakịrị ọmụmụ. Ọ dị mkpa iji kpachara anya mgbe ị na-atụle iji clomiphene eme ihe, karịsịa na enweghị ihe akaebe doro anya. Ọzọkwa, ọ bụ ihe amamihe dị na ya ịkpọtụrụ onye ọkachamara ahụike tupu itinye clomiphene n'ime usoro steroid.
Nkwanye:
nwoke
A na-eji Clomiphene na pct, na dose nke 50-100 mg kwa ụbọchị maka ụbọchị 30 iji weghachi mmepụta testosterone eke na ọkwa nkịtị. A na-ewerekarị ojiji a dị ka ihe kacha mma dị ka akụkụ nke mmemme mgbake gachara (lee ọgwụgwọ PCT)
ụmụ nwanyị na-eme egwuregwu
A na-eji Clomid eme ihe mgbe ụfọdụ iji belata estrogen tupu ịsọ mpi n'asọmpị ahụ. N'ọnọdụ ụfọdụ, nke a nwere ike inye aka na-efunahụ abụba ma kwalite mmepe akwara, ọkachasị n'ebe nsogbu ụmụ nwanyị nọ dị ka isi na apata ụkwụ. Agbanyeghị, ọgwụ a na-enwekarị mmetụta na-enye nsogbu n'ahụ ụmụ nwanyị premenopausal, yabụ na ọ bụghị nnukwu mkpa n'etiti otu a.
Clomiphene, nke a na-ejikarị eme ihe maka nsogbu ọmụmụ nwanyị, enwetawo nlebara anya maka ojiji ọ na-eji ndị ikom nwere ọnụ ọgụgụ spam dị ala yana dị ka ọgwụ na-edozi testosterone maka ndị na-arụ ọrụ nwoke. Usoro ya na-arụ ọrụ gụnyere ịkpali nzuzo nke gonadotropins, nke na-eme ka ovulation na ụmụ nwanyị na mmepụta testosterone na ụmụ nwoke. Otú ọ dị, ịdị irè na nchekwa nke clomiphene na ụmụ nwoke chọrọ nyocha ọzọ.
Cheta ịkpọtụrụ anyị maka nnyefe ngwa ngwa!
Nkọwapụta
