Dexamethasone ntụ ntụ Dexamethasone Raw Materials Dexamethasone CAS 50-02-2

Aha ngwaahịa Dexamethasone
Ọdịdị Ọcha ma ọ bụ ọ fọrọ nke nta ka ọ bụrụ ntụ ntụ crystalline ọcha
CAS Mba. 50-02-2
Usoro ọgwụ C22H29FO5
Ibu arọ molekụla 392.46
Ebe mgbaze 262-264 Celsius C (ọkụ)
Ebe esi nri 568.2oC na 760 mmHg
Njupụta 76 Celsius (C=1, Dioxane) Ntugharị pụrụ iche 75° (c=1, dioxane)

Kpọtụrụ anyị

nkọwa ngwaahịa

Nkọwa zuru ezu

Dexamethasone bụ ọcha ma ọ bụ ihe fọrọ nke nta ka ọ bụrụ kristal ntụ ntụ, enweghị isi, ọ na-agbaze ntakịrị na methanol, ethanol, acetone, ma ọ bụ dioxane, soluble ntakịrị na chloroform, soluble dị ntakịrị na ether, na ọ fọrọ nke nta ka ọ bụrụ nke a na-esighị ike na mmiri.

Dexamethasone, nke a makwaara dị ka Flamethasone, flumeprednisolone, desamethasone, bụ hormone glucocorticoid. Ihe ndị sitere na ya gụnyere hydrocodesone, prednisone na ndị ọzọ, mmetụta ọgwụ ya bụ nke kachasị mgbochi mkpali, mgbochi nsị, mgbochi allergies, mgbochi rheumatism, ọgwụgwọ ọgwụgwọ. ọtụtụ ebe.

1.Anti-inflammatory mmetụta:Dexamethasone nwere ike ibelata ma gbochie mmeghachi omume anụ ahụ na mbufụt, si otú ahụ ibelata ngosipụta nke mbufụt. enzymes, na njikọ na ntọhapụ nke chemical mediators nke mbufụt.

2.Immunosuppressive mmetụta: gụnyere igbochi ma ọ bụ igbochi cell-mediated dịghịzi nzaghachi, egbu oge mmeghachi omume nfụkasị, ibelata ọnụ ọgụgụ nke T lymphocytes, monocytes, na eosinophils, na ibelata ike njikọ nke immunoglobulins na cell elu receptors., na-egbochi njikọ na mwepụta. nke interleukins, si otú ahụ ibelata mgbanwe nke T lymphocytes n'ime lymphoblasts na ibelata mgbasawanye nke isi dịghịzi nzaghachi.Ọ nwere ike ibelata ngafe nke mgbochi ọrịa site na akpụkpọ ahụ okpuru ulo na ibelata ịta nke complement components na immunoglobulins.

Ngwa

1.Ọ nwere ike ịkpali adenylate cyclase, na-egbochi phosphodiesterase, na-abawanye ọkwa CAMP, si otú ahụ na-amụba mmetụta nke ndị na-anabata beta nke bronchi na ọgwụ adrenergic na theophylline, na-egosipụta mmetụta antispasmodic bronchial n'ụzọ na-apụtaghị ìhè. bronchospasm, na-ebelata mkpọchi nke bronchi na edema, na ibelata imi imi.

2.A na-eji agwọ ọrịa nrịanrịa: dị ka dermatitis nfụkasị, ọgwụ na-akpata dermatitis (ọgwụ ọgwụ), ọrịa serum, rhinitis, mmeghachi omume ọgwụ, urticaria, purpura allergies, wdg.

3.Shock: Enwere ike iji ya dị ka ọgwụgwọ inyeaka maka ujo septic, ujo anaphylactic na cardiogenic ujo kpatara nnukwu myocardial infarction ma ọ bụ myocardial conduction ngọngọ.

4.Toxic ọrịa: Ọ nwere ike ibelata mgbaàmà nke nsi nke nje bacteria na nje na-efe efe na-akpata, na-enwekwa ezigbo antipyretic mmetụta.

5.Ulcerative colitis: Ejiri ya na Xilei Powder, wdg dị ka enema njigide, ọ nwere ike ịkwụsị mgbaàmà.

6.Assist na nchoputa nke hypercortisolism:Ime a dexamethasone suppression test nwere ike inye aka na nchoputa nke ọrịa a.

7.dị iche iche mkpali ọrịa dị ka localized enteritis, ụkwara nta maningitis, uveitis, thyroiditis, ụkwara nta, trichinellosis, nfụkasị otitis externa, ọrịa otitis externa, wdg.