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Leuprorelin Hormone Therapy maka Prostate na ara ara
Leuprorelin Hormone Therapy maka Prostate na ara ara
Leuprorelin Hormone Therapy maka Prostate na ara ara

Leuprorelin Hormone Therapy maka Prostate na ara ara

Ọnụahịa ntụaka: USD 30-100

  • Aha ngwaahịa Leuprorelin
  • CAS Mba. 53714-56-0
  • Njupụta 1.44
  • Ebe mgbaze 150-155 Celsius C
  • Ebe esi nri 1720.5°C na 760 mmHg
  • MF C59H84N16O12
  • MW 1269.473
  • Ntụgharị ntụgharị 1.681
  • ebe mgbari 994.3°C
Kpọtụrụ anyị
nkọwa ngwaahịa

Nkọwa zuru ezu

Leuprorelin, nke a makwaara dị ka Lupron ma ọ bụ Prostap, bụ ọgwụgwọ hormone a na-eji agwọ ọrịa prostate na ọrịa ara ara. Ọ bụ nke otu ọgwụ a na-akpọ gonadotropin-na-ahapụ homonụ (GnRH) agonists. N'edemede a, anyị ga-elekwasị anya na ojiji ya na ọgwụgwọ prostate na ọrịa ara ara.

Ọgwụgwọ Ọrịa Cancer Prostate:
A na-ejikarị Leuprorelin agwọ ọrịa kansa prostate dị elu. Ọ na-arụ ọrụ site n'iwetu ọkwa testosterone nke testicles na-emepụta. Mkpụrụ ndụ cancer prostate na-adabere na testosterone maka uto, ya mere ibelata ọkwa ya nwere ike ibelata ọrịa kansa ma ọ bụ belata uto ya. Nlekọta nke leuprorelin na-enyere aka ijikwa mgbaàmà ndị metụtara ọrịa kansa prostate dị elu ma na-eme ka ndụ onye ọrịa dịkwuo mma.

Ọgwụgwọ ọrịa kansa ara:
A na-ejikwa Leuprorelin na-agwọ ọrịa ụfọdụ ụdị ọrịa kansa ara. A na-eji ya eme ihe n'ọnọdụ ebe mkpụrụ ndụ kansa nwere estrogen receptors (ER positive) na onye ọrịa ahụ agabigaghị nsọ. Leuprorelin na-ebelata ogo estrogen n'ime ahụ site na igbochi mmepụta ya na ovaries. Nke a dị oké mkpa n'ihi na ọkwa dị elu nke estrogen nwere ike ịkwalite uto nke mkpụrụ ndụ cancer ara. Enwere ike iji leuprorelin naanị ya ma ọ bụ yana yana usoro ọgwụgwọ homonụ ndị ọzọ iji jikwaa ọrịa ara ara nke ọma.


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Central Precocious Puberty:

A na-eji injection Leuprorelin, nke a maara dị ka Lupron Depot-PED, na ụmụaka ndị dị afọ 2 na karịa maka ọgwụgwọ Central precocious puberty (CPP). CPP bụ ọnọdụ nke ụmụ agbọghọ (na-abụkarị ndị na-erubeghị afọ 8) na ụmụ nwoke (na-erubeghị afọ 9) na-abanye n'oge uto. Leuprorelin na-enyere aka ịhazi oge ntolite site n'ibelata uto ọkpụkpụ ngwa ngwa na mmepe nke njirimara mmekọahụ jikọtara na CPP.


Ojiji ụlọ ọgwụ ndị ọzọ:

A na-eji injection Leuprorelin, nke a makwaara dị ka Lupron Depot, na ọgwụgwọ endometriosis na anaemia kpatara fibroids uterine. Ọ na-arụ ọrụ site n'ibelata ọkwa nke ụfọdụ homonụ na ahụ, na-enye ahụ efe pụọ na mgbaàmà dị ka mgbu, ịdị arọ ma ọ bụ oge nsọ nsọ, na anaemia. Na mgbakwunye, enwere ike iji leuprorelin dị ka ọgwụgwọ tupu ọgwụgwọ tupu ịwa ahụ endometrial, ebe ọ na-eme ka endometrium dị nro, na-ebelata edema, na-eme ka usoro ịwa ahụ dị mfe.


Pharmacokinetics:
Leuprorelin acetate adịghị arụ ọrụ mgbe a na-e ya ọnụ, kama a na-enye ya site na ntụtụ subcutaneous ma ọ bụ intramuscular. Na-eso otu ịgba ọgwụ mgbochi subcutaneous nke 3.75 mg, a na-enweta mkpokọta plasma kacha elu n'ime ụbọchị 1 ruo 2, yana ọkwa 1 ruo 2 ng / ml. Na ọgwụgwọ ọrịa cancer prostate, a na-enye injections subcutaneous nke 3.75 mg kwa izu anọ maka ngụkọta nke injections 3 iji nweta mkpokọta plasma na-adịgide adịgide nke 0.1 ruo 1 ng/ml. Leuprorelin bụ metabolized n'ime ihe anọ na-emebi emebi n'ime ahụ ma na-esi na akụrụ pụta ya.

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Mmechi:
Leuprorelin, GnRH agonist, bụ ọgwụgwọ hormone bara uru nke a na-eji na-agwọ ọrịa prostate na ọrịa ara ara, yana Central precocious puberty, endometriosis, na anaemia kpatara fibroids uterine. Site na ibelata ọkwa testosterone ma ọ bụ estrogen, leuprorelin na-enyere aka ịchịkwa uto na mgbaàmà metụtara ọnọdụ ndị a. Nlekọta nke leuprorelin chọrọ nlekọta ahụike yana nleba anya mgbe niile iji hụ na ọ dị irè ma jikwaa mmetụta ọ bụla nwere ike ime.

Cheta ịkpọtụrụ anyị maka nkọwa ngwugwu na ụdị mbupu, anyị ga-enye ọrụ nhazi OEM / ODM ọkachamara.

Nkọwapụta

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