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Memantine HCl 99% dị ọcha na-agwọ ọrịa Alzheimer Factory Supply
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Memantine hydrochloride, nke Merz mepụtara na Germany, bụ ọgwụ ọhụrụ e bu n'obi mee maka ọgwụgwọ mgbaka. Ọ na-eme dị ka onye na-anabata N-methyl-D-aspartate (NMDA), na-egbochi ndị na-anabata NMDA ma na-ebelata hyperexcitability nke glutamate. Usoro a na-achọ ịkwalite ọrụ ọgụgụ isi, gbochie apoptosis, na ịkwalite ebe nchekwa. Pethidine hydrochloride kwadoro site na European Committee for Patented Medicinal Products (CPMP) maka ọgwụgwọ ọrịa Alzheimer dị oke ma dị njọ na 2002. Nnyocha ndị ọzọ egosiwokwa na ọ dị irè na ndị ọrịa nwere ọrịa Alzheimer dị nro ma dị nro.
Memantine hydrochloride, ihe na-arụ ọrụ na pethidine hydrochloride, bụ mmekọ na-agafeghị oke, onye na-emegide NMDA na-adịghị asọmpi. Ọ bụ ezie na ngwa ya bụ isi bụ ọgwụgwọ ọrịa Alzheimer, a mụọla ya nke ọma ma jiri ya mee ihe maka nsogbu ndị ọzọ na-ahụ maka usoro ụjọ ahụ dị ka Akwụkwụ na-adọ, migraines, na ọnọdụ uche gụnyere ọrịa bipolar na schizophrenia. Dementia ka bụ isi ihe a na-elekwasị anya na ngwa memantine, ma egosila ọkwa dị iche iche nke uru na ọrịa Alzheimer, vaskụla dementia, na dementia na Lewy ozu. Ọ bụghị naanị na ọ na-eme ka ọrụ ọgụgụ isi dịkwuo mma kamakwa ọ na-ekwukwa ihe mgbaàmà omume na nke uche nke dementia (BPSD), dị ka ịhụ anya, aghụghọ, mkpasu iwe, mkpasu iwe, na mgbakasị ahụ.
Na mgbakwunye na mmetụta ya na dementia, a nyochala memantine maka mmetụta ọ na-enwe na nsogbu akwara ozi ndị ọzọ. Ndị ọrịa nwere Akwụkwụ na-enwekarị ụkọ ọgụgụ isi, ma memantine egosila ikike ibelata mperi ndị a. Ọzọkwa, ọrịa Alzheimer n'onwe ya bụ ihe dị ize ndụ maka ọdịdọ, na ndị nwere ọrịa ahụ nọ n'ihe ize ndụ dị elu nke ịmalite ọrịa akwụkwụ ma e jiri ya tụnyere ndị na-enweghị Alzheimer. Site na igbochi neuroexcitotoxicity jikọtara ya na NMDA nnabata hyperactivation, memantine nwere ike inwe mmetụta antiepileptik.
Ọzọkwa, a mụọla memantine n'ihe gbasara ọgwụgwọ radieshon nke ụbụrụ dum (WBRT), mmerụ ahụ ụbụrụ (TBI), na ọrịa strok. WBRT nwere ike bute nrụrụ aka nke uche, na memantine egosila na ọ na-egbu oge mmalite ya ma melite ọrụ ọgụgụ isi. Ngwongwo ọgwụ pụrụ iche nke memantine emewo ka nyocha ya n'ọtụtụ nsogbu akwara ozi.
Nnyocha e mere n'oge na-adịbeghị anya atụwo aro ka enwere ike itinye memantine n'ịbelata mmetụta neurotoxic nke COVID-19 na igbochi mmegharị nje, na-egosi uru ụlọ ọgwụ na-agbasawanye.
Memantine hydrochloride, akpan akpan ihe na-arụ ọrụ memantine hydrochloride, egosila ịdị irè n'ọgwụgwọ mgbaka, ọkachasị ọrịa Alzheimer. Usoro ya pụrụ iche dị ka onye na-emegide ndị na-anabata NMDA na-enye ohere maka mmelite na ọrụ ọgụgụ isi na njikwa nke àgwà na nke mmetụta uche na-ejikọta na dementia. Ọzọkwa, memantine na-egosi nkwa na nsogbu akwara ozi ndị ọzọ dị ka Akwụkwụ na-adọ, migraines, na post-radiation cognitive imperment. Nchọpụta na-aga n'ihu na-aga n'ihu na-enyocha uru ahụike nke memantine nwere na ọnọdụ akwara ozi dị iche iche.
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