Ndị nnọchi anya Rosuvastatin na-agwọ ọrịa dyslipidemia

Rosuvastatin na-egbochi enzyme hydroxymethylglutaryl-CoA reductase n'ime imeju, nke na-ebelata njikọ cholesterol ma na-ebelata cholesterol ọbara na triglyceride. Ọzọkwa, Rosuvastatin na-abawanye nnabata imeju na nbibi nke lipoprotein cholesterol dị obere (LDL-C), ebe ọ na-ebulikwa ọkwa cholesterol nke lipoprotein dị elu (HDL-C). Na mgbakwunye na mmetụta iwetulata lipid ya, egosila Rosuvastatin nwere mgbochi atherosclerotic, mgbochi mkpali, antioxidant, plaque stabilizing na mma ọrụ endothelial.

A na-emepụta Rosuvastatin site na gbaa ụka Aspergillus terreus ma ọ bụ site na njikọ kemịkalụ. Ozugbo etinyere ya, a na-emegharị ya nke ukwuu n'ime imeju wee ghọọ metabolites dị iche iche, gụnyere metabolites na-arụ ọrụ nke na-egbochi HMG-CoA reductase. A na-ebupụ ọgwụ ahụ na metabolites ya n'ụzọ bụ isi na nsị, na-ewepụta ntakịrị ntakịrị na mmamịrị.