Nkọwa zuru ezu
Tadalafil bụ ọcha na-acha ọcha na-acha ọcha crystalline ntụ ntụ.Ọ fọrọ nke nta ka ọ bụrụ ihe a na-adịghị ahụkebe na mmiri, na-egosipụta naanị ntakịrị solubility, ma na-edozi ya na mmanya na-aba n'anya.
Ọrụ bụ isi nke Tadalafil bụ ịgwọ ọrịa erectile site n'ịba ụba ọbara na amụ n'oge mkpali mmekọahụ. Ọ na-enweta nke a site na igbochi enzyme phosphodiesterase ụdị 5 (PDE5), nke bụ maka mmebi nke cyclic guanosine monophosphate (cGMP) na corpus cavernosum. Site na igbochi PDE5, tadalafil na-enye ohere maka vasodilation ogologo oge na ịba ụba nke ọbara, nke na-enyere ndị ikom nwere nkwarụ erectile aka iji nweta ma kwado ụlọ. ruo awa 36, na-enweta ya aha otutu "ọgwụ izu ụka."
A na-egosi Tadalafil n'ụzọ bụ isi maka ọgwụgwọ nke dysfunction erectile (ED) na ndị okenye. Ọ dị n'ụdị mbadamba maka nchịkwa ọnụ, n'ụdị doses sitere na 2.5 mg ruo 20 mg, dabere na mkpa onye ọrịa na ọnọdụ a na-agwọ ya. Usoro mmalite nke akwadoro maka ọtụtụ ndị ọrịa bụ 10 mg, nke a na-ewere tupu enwee mmekọahụ na-atụ anya ya, yana nri ma ọ bụ na-enweghị. Enwere ike ịhazi dose ahụ dabere na ntachi obi na nzaghachi onye ọ bụla. Na mgbakwunye na iji ya mee ihe maka nkwụsị nke erectile, a kwadoro tadalafil maka ọgwụgwọ nke ihe ịrịba ama na mgbaàmà nke hyperplasia prostate benign (BPH), ọnọdụ nke nnukwu prostate gland na-ebuwanye ibu. Mgbe BPH na-esonyere na arụ ọrụ erectile, tadalafil nwere ike inye uru abụọ site n'ịgbasa ọnọdụ abụọ ahụ n'otu oge.
Ọzọkwa, a na-eji tadalafil iji jikwaa ọbara mgbali elu nke akpa ume (PAH) na ma ndị nwoke ma ndị nwanyị. N'ime ngwa a, ọ na-enyere aka melite ikike mmega ahụ na igbu oge na-akawanye njọ nke ọrịa ahụ.
N'ikpeazụ, tadalafil bụ ọcha na-acha ọcha na-acha ọcha crystalline ntụ ntụ na-enwe oke solubility, nke a na-ejikarị agwọ ọrịa erectile, hyperplasia prostate na-adịghị mma, na ọbara mgbali elu pulmonary arterial. Dị ka onye na-egbochi PDE5, ọ na-eme ka mmụba ọbara na-eruba n'akụkụ ahụ dị iche iche, karịsịa amụ, nke na-eme ka ọrụ erectile dịkwuo mma. Na mgbakwunye, ogologo oge ọ na-arụ ọrụ na-eme ka ọ dị iche na ọgwụ ndị ọzọ na klaasị ya, na-enye mgbanwe na nhụsianya maka ndị mmadụ na-achọ ọgwụgwọ maka ED.
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