Triptorelin, decapeptide sịntetik na analog nke homonụ na-ahapụ gonadotropin eke (GnRH), enwetala nkwanye ugwu dị ukwuu na ngalaba ahụike. A na-eji ya eme ihe ngosi dị iche iche, gụnyere ọgwụgwọ endometriosis, fibroids, ọrịa kansa prostate, oge ntozu oke, na enweghị ọmụmụ. Triptorelin na-arụ ọrụ site na mbụ na-akpali akpali nzuzo nke gonadotropins na emesia na-agbadata ndị na-anabata gonadotropin na-ewepụta homonụ, na-ebute mbelata ntọhapụ gonadotropin ogologo oge.
Triptorelin na-egosipụta ọtụtụ mmetụta ọgwụgwọ. N'ime ụmụ nwanyị, a na-eji ya ejikwa endometriosis, fibroids uterine, na enweghị ọmụmụ. Nlekọta Triptorelin na-aga n'ihu na-egbochi mmepụta nke estradiol nke ọma, na-eduga na nkwụsị nke anụ ahụ ectopic endometrial na endometriosis. Na mgbakwunye, ọmụmụ egosila mbelata dị ukwuu na nha fibroids uterine, na ọtụtụ ndị ọrịa na-enwe amenorrhea mgbe ọnwa mbụ nke ọgwụgwọ gasịrị. Maka enweghị ọmụmụ, triptorelin na-egbochi nzuzo nke gonadotropins, na-eme ka mmepụta nke follicle dị mma ma na-amụba ọnụ ọgụgụ nke follicles, si otú ahụ na-eme ka ohere nke usoro ọmụmụ aka na-aga nke ọma dị ka in vitro Fertilization.
N'ime ụmụ nwoke, a na-ejikarị triptorelin agwọ ọrịa kansa prostate. Ọ na-eme site na mbido ịba ụba homonụ luteinizing ọbara (LH) na ọkwa follicle-stimulating hormone (FSH), na-esote mbelata nke homonụ ndị a yana mbelata ọkwa testosterone ọbara na-esote. Mbelata a na ọkwa testosterone na-enyere aka n'ịgwọ ọrịa cancer prostate na mgbaàmà ndị metụtara ya. Ngwunye nke Triptorelin arụkwara ọrụ nke ọma n'ịgwọ oge ntozu oke, na-egbochi hypersecretion pituitary nke gonadotropins na ịhazi ọkwa homonụ.
Usoro nke triptorelin na-agụnye ma nkwụsị nke secretion gonadotropin na mgbochi gonadotropic kpọmkwem site na-eme ka ndị na-anabata GnRH dị elu. Ọmụmụ anụmanụ na ụmụ mmadụ egosila mmetụta mgbochi nke triptorelin na-adịghị ala ala iji na-emepụta ihe nzuzo nke gonadotropin, na-eduga na nkwụsị nke testicular na ovarian ọrụ. A na-egosipụtakwa ịdị irè Triptorelin site na mmụba ụlọ ọgwụ na mgbaàmà dị ka dysmenorrhea, mgbu pelvic na-adịghị ala ala, na mgbu n'oge mmekọahụ.
Anyị na-enye ihe ngwọta dị iche iche ahaziri maka gị ịhọrọ
Ọgwụ mgbochi Triptorelin: 0.1 mg / 1 ml.
Ọgwụ mgbochi agbatị Triptorelin: 3.75 mg; 11.25 mg; 22.5 mg.
Triptorelin pamoate maka ịgba ọgwụ: 15 mg kwa karama (nwere 1 karama nke ihe mgbaze 2 ml). Ọ bụrụ na ị nwere mkpa ndị ọzọ, ị nwekwara ike ịkpọtụrụ anyị na anyị ga-enye gị ọrụ nhazi ngwa ngwa na nke ziri ezi.
Dị ka analọg gonadotropin nwere ike, Triptorelin na-enye ọtụtụ ngwa ọgwụgwọ maka ma nwoke ma nwanyị. Ikike ya ịchịkwa ọkwa hormone na igbochi ihe nzuzo nke gonadotropin egosila na ọ dị irè n'ịchịkwa ọnọdụ ndị dị ka endometriosis, uterine fibroids, cancer prostate, ntozu oke, na enweghị ọmụmụ. Site na ịdị irè ya na ịdị irè ya, triptorelin na-aga n'ihu na-enye aka nke ukwuu na ngalaba nke ọgwụ ọmụmụ na oncology. Ịghọta usoro ihe omume na nkwadebe dịnụ nke triptorelin na-enye ndị ọkachamara ahụike aka ịhazi atụmatụ ọgwụgwọ maka mkpa onye ọrịa ọ bụla.
