Ko Rosuvastatin te kaihoko antilipemic ko Rosuvastatin te rongoa i te dyslipidemia

Ka aukati a Rosuvastatin i te enzyme hydroxymethylglutaryl-CoA reductase i roto i te ate, e whakaiti ana i te whakahiato cholesterol me te whakaheke i nga taumata cholesterol me te triglyceride serum. I tua atu, ka whakanui a Rosuvastatin i te tango a te ate me te pakaru o te lipoprotein cholesterol iti (LDL-C), me te whakanui ake i nga taumata o te lipoprotein cholesterol teitei (HDL-C). I tua atu i ona hua whakaheke lipid, kua whakaatuhia te Rosuvastatin he anti-atherosclerotic, anti-inflammatory, antioxidant, whakapumau tohu, me te whakapai ake i nga mahi endothelial.

Ko te Rosuvastatin ka hangaia ma te FERMENTATION o Aspergillus terreus, ma te whakahiato matū ranei. I muri i te whakaurunga, ka kaha te whakakoi i roto i te ate ka huri ki nga momo metabolites, tae atu ki nga metabolites kaha e aukati ana i te HMG-CoA reductase. Ko te raau taero me ona metabolites ka tukuna ki roto i nga kohungahunga, me te iti o te waahanga ka tukuna ki roto i te mimi.