Kufotokozera Mwatsatanetsatane
Clomiphene, mankhwala ovomerezeka ndi FDA omwe amagwiritsidwa ntchito makamaka pazovuta za kubereka kwa akazi, akhala akuwoneka kuti ndi osayenera kwa amuna. Komabe, asing'anga otsogola apeza momwe angagwiritsire ntchito clomiphene mwa amuna omwe ali ndi umuna wochepa chifukwa cha majini kapena kugwiritsa ntchito ma steroid. Kuphatikiza apo, omanga thupi amuna ayamba kugwiritsa ntchito clomiphene ngati mankhwala osamalira testosterone kuti apititse patsogolo kukula kwa minofu. Tikupereka chithunzithunzi cha machitidwe a clomiphene, zotsatira zake pa mlingo wa mahomoni, ndi ubwino wake ndi zoopsa zake kwa amuna.
Clomiphene amadziwika kuti amakhudza estrogen axis m'thupi, ngakhale kuti njira yake yeniyeni yochitira zinthu imakhalabe yodabwitsa. Imalumikizana ndi ma estrogen receptors m'magulu osiyanasiyana, kuphatikiza hypothalamus, pituitary gland, ovaries, endometrium, nyini, khomo lachiberekero, adrenal glands, zotumphukira adipose minofu, chiwindi, ndi ma testes. Kwa amayi, clomiphene imagwira ntchito kwambiri pa hypothalamus ndi pituitary gland, zomwe zimalimbikitsa kutulutsidwa kwa gonadotropin-release hormone (GnRH), follicle-stimulating hormone (FSH), ndi luteinizing hormone (LH). Kukondoweza uku kumalimbikitsa ovulation. Mwa amuna, clomiphene imagwiranso ntchito pa hypothalamus ndi pituitary gland, zomwe zimapangitsa kuti testosterone ndi umuna zichuluke.
Mosiyana ndi zomwe anthu ambiri amakhulupirira, clomiphene sichichepetsa milingo ya estrogen m'thupi. M'malo mwake, imatha kulimbikitsa kutulutsa kwa estrogen kumlingo wina mwa amuna. Ndikofunikira kwa anthu omwe amagwiritsa ntchito clomiphene, makamaka omanga thupi lachimuna, kuti aziyang'anira ma testosterone ndi estradiol kuti apewe zotsatira zoyipa monga gynecomastia (kukulitsa mawere amphongo).
Amuna omanga thupi nthawi zambiri amagwiritsa ntchito clomiphene monga chothandizira pamagulu awo a steroid. Komabe, ndikofunikira kuzindikira kuti clomiphene sichimatchulidwa ngati mankhwala owonjezera masewera olimbitsa thupi ndipo ilibe zotsatira za androgenic. Kugwiritsiridwa ntchito kwa nthawi yaitali kwa clomiphene mwa amuna kwagwirizanitsidwa ndi macromastia (mabere okulirapo) ndi zotupa za testicular, ngakhale kuti kugwirizana kotsimikizika pakati pa clomiphene ndi zotsatirazi sikunakhazikitsidwe.
Ngakhale kuti clomiphene ikugwiritsidwa ntchito kwambiri ndi omanga thupi amuna ndi othamanga, mphamvu yake mwa amuna imakhalabe yosadziwika chifukwa cha maphunziro ochepa. Ndikofunikira kusamala mukaganizira kugwiritsa ntchito clomiphene, makamaka ngati palibe umboni wotsimikizika. Komanso, ndi bwino kukaonana ndi katswiri wa zachipatala musanaphatikizepo clomiphene mu regimen ya steroid.
Malangizo:
mwamuna
Clomiphene amagwiritsidwa ntchito mu pct, pa mlingo wa 50-100 mg tsiku lililonse kwa masiku a 30 kuti abwezeretse kupanga testosterone yachilengedwe kumagulu abwino. Kugwiritsa ntchito uku kumawonedwa ngati koyenera kwambiri ngati gawo la pulogalamu yobwezeretsa pambuyo pozungulira (onani PCT Chithandizo)
othamanga achikazi
Clomid nthawi zina amagwiritsidwa ntchito kuchepetsa estrogen asanapikisane nawo mpikisano womanga thupi. Nthawi zina, izi zingathandize kutaya mafuta ndikulimbikitsa kukula kwa minofu, makamaka m'madera ovuta a amayi monga matako ndi ntchafu. Komabe, mankhwalawa nthawi zambiri amakhala ndi zotsatira zoyipa kwambiri mwa amayi omwe ali ndi vuto losiya kusamba ndipo motero sakufunika kwambiri pakati pa gululi.
Clomiphene, yomwe imagwiritsidwa ntchito makamaka pazovuta za kubereka kwa akazi, yapeza chidwi pakugwiritsa ntchito kwake mwa amuna omwe ali ndi umuna wochepa komanso ngati mankhwala osamalira testosterone kwa omanga thupi amuna. Kachitidwe kake kakuchitapo kanthu kumaphatikizapo kulimbikitsa katulutsidwe ka gonadotropins, zomwe zimalimbikitsa ovulation mwa amayi ndi kupanga testosterone mwa amuna. Komabe, mphamvu ndi chitetezo cha clomiphene mwa amuna zimafuna kufufuza kwina.
Kumbukirani kulumikizana nafe kuti mutumizidwe mwachangu!
Kufotokozera
