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Zogulitsa Magulu
Zamgululi
Mapiritsi a Lenopril Amathandizira Kuwongolera Kuthamanga kwa Magazi ndi Thanzi Lamtima

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Tirzepatide Dual GLP-1 ndi GIP Receptor Agonist for Weight Management and Glycemic Control

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Ostarine (MK-2866) SARM Yosiyanasiyana ya Kukula kwa Minofu, Kutaya Mafuta, ndi Kubwezeretsanso Thupi

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Leuprorelin Hormone Therapy for Prostate ndi Khansa ya M'mawere
Leuprorelin Hormone Therapy for Prostate ndi Khansa ya M'mawere
Leuprorelin Hormone Therapy for Prostate ndi Khansa ya M'mawere

Leuprorelin Hormone Therapy for Prostate ndi Khansa ya M'mawere

Mtengo wolozera: USD 30-100

  • Dzina la malonda Leuprorelin
  • CAS No. 53714-56-0
  • Kuchulukana 1.44
  • Malo osungunuka 150-155 ° C
  • Malo otentha 1720.5°C pa 760 mmHg
  • MF Chithunzi cha C59H84N16O12
  • MW 1269.473
  • Refractive index 1.681
  • pophulikira 994.3°C
Lumikizanani nafe
tsatanetsatane wazinthu

Kufotokozera Mwatsatanetsatane

Leuprorelin, yomwe imadziwikanso kuti Lupron kapena Prostap, ndi mankhwala a mahomoni omwe amagwiritsidwa ntchito pochiza prostate ndi khansa ya m'mawere. Ndi m'gulu la mankhwala otchedwa gonadotropin-releasing hormone (GnRH) agonists. M'nkhaniyi, tiona momwe amagwiritsidwira ntchito pochiza khansa ya prostate ndi khansa ya m'mawere.

Chithandizo cha Khansa ya Prostate:
Leuprorelin imagwiritsidwa ntchito kwambiri pochiza khansa ya prostate yapamwamba. Zimagwira ntchito pochepetsa mlingo wa testosterone wopangidwa ndi machende. Maselo a khansa ya prostate amadalira testosterone kuti ikule, kotero kuchepetsa milingo yake kumatha kuchepetsa khansa kapena kuchepetsa kukula kwake. Kayendetsedwe ka leuprorelin kumathandiza kuthana ndi zizindikiro zokhudzana ndi khansa ya prostate yapamwamba komanso kuwongolera moyo wa wodwalayo.

Chithandizo cha Khansa ya M'mawere:
Leuprorelin imagwiritsidwanso ntchito pochiza mitundu ina ya khansa ya m'mawere. Amagwiritsidwa ntchito makamaka pamene maselo a khansa ali ndi ma estrogen receptors (ER positive) ndipo wodwalayo sanadutse kusamba. Leuprorelin imachepetsa mlingo wa estrogen m'thupi mwa kupondereza kupanga kwake m'matumbo. Izi ndizofunikira chifukwa kuchuluka kwa estrogen kumatha kulimbikitsa kukula kwa maselo a khansa ya m'mawere. Leuprorelin ikhoza kuperekedwa yokha kapena kuphatikiza ndi mankhwala ena a mahomoni kuti athe kuthana ndi khansa ya m'mawere.


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Central Precocious Puberty:

Jakisoni wa Leuprorelin, womwe umadziwika kuti Lupron Depot-PED, umagwiritsidwa ntchito mwa ana azaka za 2 kapena kuposerapo pochiza kutha msinkhu kwapakati (CPP). CPP ndi mkhalidwe womwe atsikana (nthawi zambiri ochepera zaka 8) ndi anyamata (nthawi zambiri ochepera zaka 9 zakubadwa) amayamba kutha msinkhu msanga. Leuprorelin imathandiza kuwongolera nthawi ya kutha msinkhu mwa kuchepetsa kukula kwa mafupa ndi kukula kwa makhalidwe ogonana okhudzana ndi CPP.


Ntchito Zina Zachipatala:

Jakisoni wa Leuprorelin, womwe umadziwikanso kuti Lupron Depot, umagwiritsidwa ntchito pochiza endometriosis ndi kuchepa kwa magazi m'thupi chifukwa cha uterine fibroids. Zimagwira ntchito pochepetsa kuchuluka kwa mahomoni ena m'thupi, kupereka mpumulo kuzizindikiro monga kupweteka, kusamba kwakukulu kapena kusakhazikika, komanso kuchepa kwa magazi. Kuonjezera apo, leuprorelin ikhoza kugwiritsidwa ntchito ngati chithandizo chamankhwala chisanadze endometrial resection, chifukwa imachepetsa endometrium, imachepetsa edema, ndikuthandizira opaleshoni.


Pharmacokinetics:
Leuprorelin acetate siigwira ntchito ikatengedwa pakamwa ndipo m'malo mwake imaperekedwa kudzera mu jekeseni wa subcutaneous kapena intramuscular. Kutsatira limodzi subcutaneous jekeseni wa 3.75 mg, pachimake plasma ndende anafika mkati 1 kwa 2 masiku, ndi milingo 1 mpaka 2 ng/ml. Pochiza khansa ya prostate, jakisoni wocheperako wa 3.75 mg amaperekedwa milungu inayi iliyonse kwa jakisoni wa 3 kuti akwaniritse kuchuluka kwa plasma kwa 0.1 mpaka 1 ng/ml. Leuprorelin imasinthidwa kukhala zinthu zinayi zowonongeka m'thupi ndipo amatulutsidwa makamaka kudzera mu impso.

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Pomaliza:
Leuprorelin, GnRH agonist, ndi mankhwala ofunikira omwe amagwiritsidwa ntchito pochiza khansa ya prostate ndi khansa ya m'mawere, komanso kutha msinkhu, endometriosis, ndi kuchepa kwa magazi m'thupi chifukwa cha uterine fibroids. Pochepetsa milingo ya testosterone kapena estrogen, leuprorelin imathandizira kuwongolera kukula ndi zizindikiro zomwe zimagwirizana ndi izi. Ulamuliro wa leuprorelin umafunika kuyang'aniridwa ndi achipatala ndi kuyang'anitsitsa nthawi zonse kuti zitsimikizire kuti zikugwira ntchito bwino ndikuwongolera zotsatira zilizonse zomwe zingakhalepo.

Kumbukirani kutilumikizana nafe kuti mupeze mafomu atsatanetsatane ndi kutumiza, tidzapereka ntchito zaukadaulo za OEM/ODM.

Kufotokozera

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