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Zogulitsa Magulu
Zamgululi
Mapiritsi a Lenopril Amathandizira Kuwongolera Kuthamanga kwa Magazi ndi Thanzi Lamtima

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Telmisartan Bwino antihypertensive Kuteteza aimpso

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Flumazenil A Selective GABAA Receptor Antagonist ndi Therapeutic Applications

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Trametinib Kinase Inhibitor Kutsata BRAF V600 Mutation-Positive Cancers

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YK-11 SARM Yamphamvu Yomanga Minofu, Kupeza Mphamvu, ndi Myostatin Inhibition

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0102030405
Vasopressin Multifaceted Hormone Regulating Fluid Balance
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Mtengo Wothandizira: USD 40-100

  • Dzina lazogulitsa Vasopressin
  • CAS No. 11000-17-2
  • Maonekedwe White Lyophilized ufa
  • MF Zithunzi za C46H65N13O12S2
  • MW 1056.22
  • Malingaliro a kampani EINECS 234-236-2
  • Kuchulukana 1.31g/cm3
Lumikizanani nafe
tsatanetsatane wazinthu

Kufotokozera Mwatsatanetsatane

Vasopressin, yomwe imadziwikanso kuti antidiuretic hormone (ADH), imagwira ntchito yofunika kwambiri pakuwongolera osmolality yamadzimadzi polimbikitsa kuyamwanso kwamadzi mu impso. Hormoni iyi sikuti imangoyambitsa zotsatira za antidiuretic komanso imawonetsa vasoconstrictive properties ndipo imakhudza ziwalo zosiyanasiyana monga matumbo, ndulu, ndi chikhodzodzo. Vasopressin amagwiritsidwa ntchito pochiza uremia wapakati, polyuria pambuyo pa opaleshoni yaubongo kapena kupwetekedwa mutu, kupumula kwa minofu ya m'mimba, komanso ngati chothandizira pakuwongolera kukha magazi kwakukulu.

Vasopressin imagwira ntchito ngati chowongolera chachikulu cha osmolality yamadzimadzi powonjezera kuyamwanso kwamadzi mu impso. Powonjezera kufalikira kwa ma cell a epithelial munjira zotolera aimpso, vasopressin imathandizira kuyamwanso kwamadzi, zomwe zimapangitsa kuti pakhale antidiuretic. Kuphatikiza apo, imawonetsa mphamvu za vasoconstrictive, kutsekereza mitsempha yotumphukira, ndikupangitsa kuti matumbo, ndulu, ndi chikhodzodzo.


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Pochiza uremia wapakati, vasopressin imagwiritsidwa ntchito poyang'anira zizindikiro zomwe zimagwirizanitsidwa ndi vuto la pressin, monga kuchuluka kwa mkodzo wamadzi ndi ludzu lowonjezereka. Imathandiza kubwezeretsa bwino kwa osmolality yamadzimadzi am'thupi powonjezera kuyamwanso kwamadzi m'mitsempha yaimpso ya tubular, zomwe zimapangitsa kuchepa kwa kupanga mkodzo komanso kuchuluka kwa sodium mumkodzo.

Vasopressin imagwiritsidwanso ntchito pochiza polyuria pambuyo pa opaleshoni yaubongo kapena kuvulala kwamutu. Mwa kuwongolera kuchuluka kwa madzimadzi, vasopressin imathandizira kuchepetsa kupanga mkodzo wambiri ndikusunga madzi abwino.

Kuphatikiza apo, vasopressin imapeza ntchito pakupumula kwamatumbo am'mimba pomwe mankhwala ena alibe mphamvu. Kuthekera kwake kupangitsa vasoconstriction ndikukhudza kukhazikika kwa minofu yosalala kumapereka mpumulo pamikhalidwe ina yomwe kupumula kwa minofu kumafunika.

Mu pachimake kukha magazi chifukwa cha matenda am`mero, m`mimba thirakiti, ndi zina m`mimba thirakiti, vasopressin angagwiritsidwe ntchito ngati adjunct pa mankhwala. Mphamvu zake za vasoconstrictive zimathandiza kuchepetsa magazi komanso kukhazikika kwa wodwalayo.
Vasopressin imapangidwa pakati pa hypothalamus ngati cyclic nonapeptide. Amatenga nawo gawo mu hypothalamic-pituitary-adrenal axis ndipo amayang'anira katulutsidwe ka pituitary corticotropin powonjezera zotsatira za corticotropin-releasing factor. Kuphatikiza apo, vasopressin imagwira ntchito ngati neurotransmitter, ikuchitapo kanthu pomanga ma receptor apadera a G protein.

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Vasopressin, yomwe imadziwikanso kuti antidiuretic hormone, imagwira ntchito yofunika kwambiri pakuwongolera kuchuluka kwamadzi m'thupi. Kuthekera kwake kukopa kuyambiranso kwamadzi, vasoconstriction, ndikukhudza ziwalo zosiyanasiyana kumapangitsa kukhala hormone yosunthika yokhala ndi ntchito zambiri zochizira. Kuchokera pakuwongolera uremia wapakati ndi polyuria mpaka kuthandizira kupumula kwa minofu ya m'mimba ndikuwongolera kukha magazi kwakukulu, vasopressin imawonetsa mphamvu yake muzochitika zosiyanasiyana zachipatala.

Kufotokozera

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