Ifu ya Cisplatine Cisplatine Yera 99% Imiti ya Cisplatine

izina RY'IGICURUZWA Cisplatin
Kugaragara Ifu-Umuhondo kugeza Umuhondo wijimye wijimye
URUBANZA No. 15663-27-1
Imiti yimiti Cl2H6N2Pt
Uburemere bwa molekile 300.05
Ingingo yo gushonga 270 ℃
Ubucucike 3.7

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Cisplatin, izwi kandi ku izina ry’ubucuruzi Platinol, ni imiti ya chimiotherapie ikoreshwa mu kuvura kanseri zitandukanye.

Kugaragara: Cisplatine ni ifu yera ya kirisiti ya kirisiti yera kandi ifite impumuro mbi iranga.Birashonga cyane mumazi ariko bigashonga mubisubizo birimo chloride hamwe na solge zimwe na zimwe. imiterere yubushyuhe kugirango igumane ituze.Iyo ibitswe neza, cisplatine ikomeza ubunyangamugayo nimbaraga zayo.Yatangijwe bwa mbere mu 1844 na Alfred Werner, umuhanga mu bya shimi w’Ubusuwisi wahawe igihembo cyitiriwe Nobel muri chimie mu 1913 kubera ibikorwa bye byo guhuza ibice.Cisplatine yari nyuma yaje gukora iperereza kubishobora kuba birwanya anticancer kandi byagaragaye ko bifite akamaro mukuvura indwara mbi zitandukanye.

Imikorere nuburyo bukoreshwa: Cisplatine ishyirwa mubikorwa nkumuti wa chimiotherapie ushingiye kuri platine kandi ukaba uri mumuryango wibikoresho bya alkylating.Bikora ingaruka za anticancer mugukora imiyoboro ya covalent hamwe na ADN, bigatera ihungabana ryimikorere ya selile kandi amaherezo bigatera urupfu rwakagari. Byumwihariko. . ubwoko bwa kanseri, harimo testicular, ovarian, uruhago, umutwe nijosi, ibihaha, na kanseri y'inkondo y'umura.

Bikunze kuba muburyo bwa chimiotherapie ikomatanya kandi bigakorwa mumitsi mumavuriro iyobowe ninzobere mubuzima. Guhuza cisplatine nizindi miti ya chimiotherapeutique, nka etoposide, bleomycine, na fluorouracil, byagaragaje ingaruka zifatika mukuvura bimwe. malignancies. Usibye uruhare rwayo rwibanze mu kurwara ibibyimba bikomeye, cisplatine inakoreshwa mu kuvura ibibyimba byo mu tugingo ngengabuzima, haba nk'umuntu umwe ndetse no mu bindi biyobyabwenge bya chimiotherapie.Yagaragaje imikorere myiza mu micungire ya kanseri yandurira mu mitsi, cyane iyo ikoreshejwe ifatanije nubundi buryo bushingiye kuri platine nka etoposide na bleomycine.Ikindi kandi, cisplatine yakozweho ubushakashatsi ku buryo ishobora gukoreshwa mu bundi bwoko bwa kanseri, harimo kanseri ya Esophageal, gastric, na pancreatic kanseri.

Ubushakashatsi bukomeje gukora ubushakashatsi ku mikorere yabwo hamwe n’ubuvuzi bushya bugamije kuvura no gukingira indwara kugira ngo hongerwe imbaraga mu buvuzi no kugabanya iterambere ry’imyigaragambyo. Usibye kuvura kanseri, cisplatine yanakozweho ubushakashatsi ku buryo ishobora gukoreshwa mu buvuzi bwa hyperthermia bwaho, bukubiyemo gushyushya uduce tumwe na tumwe twa umubiri wica selile cyangwa ukarushaho kumva neza ubundi buvuzi.Muri urwo rwego, cisplatine ikoreshwa ifatanije nubushyuhe kugirango yongere ingaruka za cytotoxique muri microen ibidukikije.

Muri make, cisplatine ni imiti ya chimiotherapie ishingiye kuri platine ikora sintetike ikora ingaruka zayo za anticancer ikora ADN ihuza kandi igatera urupfu rw'uturemangingo muri kanseri ya kanseri. kanseri y'inkondo y'umura, hamwe n'ubushakashatsi burimo gukorwa bushakisha ubushobozi bwayo mu zindi ndwara mbi. Byongeye kandi, cisplatine ifite uburyo bushobora gukoreshwa mu kuvura hyperthermia kandi ikomeza kuba ikintu cy'ingenzi mu buryo bwa chimiotherapie.