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Ifu ya Dapoxetine ibinini bya Dapoxetine Gusohora imburagihe kubagabo
Ibisobanuro birambuye
Dapoxetine, CAS No 119356-77-3, hamwe na formula ya molekuline C21H23NO, ni imiti ikoreshwa mu kuvura gusohora imburagihe ku bagabo. Biboneka nkumweru kugeza kuri-ifu ya kirisiti ya kirisiti, kandi nta mpumuro nziza. Dapoxetine ifite ubushobozi buke mu mazi.
Ifu ya Dapoxetine ni ubwoko bushya bwa SSRI yihuta hamwe nigihe gito cyubuzima. Nibintu byatoranijwe bya serotonine reuptake inhibitor (SSRI). Numuti ukoreshwa mukuvura gusohora imburagihe kubagabo bafite hagati yimyaka 16 na 84.
Mu cyiciro cya II gihamya-y-igitekerezo cyakozwe na PPD, dapoxetine yerekanye ubwiyongere bugaragara bw’imibare yo gutinda gusohora iyo ugereranije na placebo.Birahita byinjira kandi bikavaho, bikavamo kwirundanya gake, kandi bifite imiti-ya farumasi itagira ingaruka kuri inshuro nyinshi.
Dapoxetine (INN, izina ryikirango Priligy), ifishi ikoreshwa cyane ni tablet, natwe dushyigikira capsules yihariye. Ubusanzwe byakozwe nka antidepressant, nyuma byaje kugaragara ko bifite akamaro keza mukuvura gusohora imburagihe (PE). Ubu bifatwa nkumuti mwiza wo gusohora imburagihe kubagabo. Dapoxetine irashobora kongera igihe cyimibonano mpuzabitsina kubagabo, bityo bikazamura imibereho yubuzima bwabo bwimibonano mpuzabitsina. Dapoxetine ihindura imiyoboro yimitsi ihagarika gufata serotonine, bityo byongera ubukana bwa serotonine muri synaps. Iki gikorwa cyemerera dapoxetine kongera igihe cyimibonano mpuzabitsina, bityo igafasha abagabo bafite ibibazo byo gusohora imburagihe. Umuti wo kuvura dapoxetine mubusanzwe ni 30mg cyangwa 60mg, ushobora guhinduka ukurikije uko umurwayi ameze. Yinjira vuba nyuma yubuyobozi bwo mu kanwa kandi bifata amasaha agera kuri 1-2 kugirango igere kuri plasma yibanze. Igice cya kabiri cyubuzima bwa dapoxetine ni amasaha agera kuri 1-2, bivuze ko ihindagurika kandi igasohoka vuba mumubiri. Mu barwayi benshi, gukoresha dapoxetine ni byiza, ariko hari ingaruka mbi zishobora kubaho, harimo kubabara umutwe, isesemi, kudasinzira, umunaniro, n'ibindi. Mbere yo gutangira dapoxetine, ugomba kuvugana na muganga wawe kugira ngo umenye ko nta ngaruka zo guhura n’abandi imiti cyangwa ubuvuzi buriho.
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