Ifu ya Dexamethasone Dexamethasone Ibikoresho Byibanze Dexamethasone CAS 50-02-2

izina RY'IGICURUZWA Dexamethasone
Kugaragara Ifu yera cyangwa hafi yera ifu ya kristaline
URUBANZA No. 50-02-2
Imiti yimiti C22H29FO5
Uburemere bwa molekile 392.46
Ingingo yo gushonga 262-264 ° C (lit.)
Ingingo yo guteka 568.2oC kuri 760 mmHg
Ubucucike 76 ° (C = 1, Dioxane) Guhinduranya byihariye 75 ° (c = 1, dioxane)

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Dexamethasone ni ifu yera cyangwa hafi yera ifu ya kristaline, idafite impumuro nziza.Birashonga gato muri methanol, Ethanol, acetone, cyangwa dioxane, bigashonga gato muri chloroform, bigashonga cyane muri ether, kandi bigashonga mumazi.

Dexamethasone, izwi kandi ku izina rya Flamethasone, flumeprednisolone, desamethasone, ni imisemburo ya glucocorticoid.Ibikomokaho birimo hydrocodeone, prednisone n'ibindi, ingaruka za farumasi zayo ni anti-inflammatory, anti-toxin, anti-allergie, anti-rheumatism, gukoresha ivuriro ni cyane.

1.Anti-inflammatory ingaruka: Dexamethasone irashobora kugabanya no gukumira igisubizo cyumubiri ku gutwika, bityo bikagabanya kwigaragaza kw’umuriro. enzymes, hamwe no guhuza no kurekura abahuza imiti yo gutwika.

2.Imunosuppressive ingaruka: harimo gukumira cyangwa kubuza ingirabuzimafatizo ziterwa na selile, gutinda kwa allergique, kugabanya umubare wa Lymphocytes T, monocytes, na eosinofile, no kugabanya ubushobozi bwo guhuza immunoglobuline kubakira bwakagari., Kandi bikabuza guhuza no kurekura. ya interleukins, bityo bigabanya ihinduka rya lymphocytes T muri lymphoblasts no kugabanya kwaguka kw’ibanze by’ubudahangarwa.Bishobora kugabanya kunyura mu bice by’umubiri binyuze mu gice cyo hasi kandi bikagabanya kwibanda ku bintu byuzuzanya na immunoglobuline.

Gusaba

1.Bishobora gushimisha adenylate cyclase, ikabuza fosifisiyose, kongera urugero rwa cAMP, bityo bikongerera ubukana bwimiti ya beta yakira imiti ya adrenergique na theophylline, no gukoresha mu buryo butaziguye ingaruka za antispasmodic bronchial.Kandi mugukoresha ingaruka zo kurwanya inflammatory na anti-allergique. bronchospasm, gabanya ubukana bwa bronchial na edema, kandi ugabanye ururenda.

2.Yakoreshejwe mu kuvura indwara za allergique: nka dermatite ya allergique, dermatite iterwa n'ibiyobyabwenge (kuruka kw'ibiyobyabwenge), indwara ya serumu, rhinite, ibiyobyabwenge, urticaria, purpura ya allergique, nibindi.

3.Isuzuma: Irashobora gukoreshwa nk'ubuvuzi bufasha kuvura septique, guhungabana kwa anaphylactique no guterwa n'umutima biterwa n'indwara ikaze ya myocardial infarction cyangwa bloc ya myocardial.

4. Indwara z'uburozi: Irashobora kugabanya ibimenyetso byuburozi buterwa na bagiteri na virusi, kandi ikagira ingaruka nziza ya antipyretike.

5.Ulcerative colitis: Yifashishijwe ifatanije na Powder ya Xilei, nibindi nkibyuma byo kugumana, birashobora kugabanya ibimenyetso.

6.Fasha mugupima hypercortisolism: Gukora ikizamini cyo guhagarika dexamethasone birashobora gufasha mugupima iyi ndwara.

7.Indwara zitandukanye ziterwa na enterineti nka enterite yaho, igituntu cya meningite, uveitis, tiroyide, igituntu, trichinellose, allergic otitis externa, otitis externa yanduye, nibindi.