Terbinafine Ifu ya Hydrochloride Ifu ya Terbinafine Hcl ibinini bya Terbinafine

izina RY'IGICURUZWA Terbinafine
Kugaragara Ifu ya kirisiti yera
URUBANZA No. 91161-71-6
Imiti yimiti C21H25N
Uburemere bwa molekile 291.438
Ingingo yo gushonga 203-205 ° C.
Ingingo yo guteka 417.9 ± 33.0 ° C (Biteganijwe)
Ubucucike 1.007 ± 0.06 g / cm3 (Biteganijwe)

Twandikire

ibicuruzwa birambuye

Ibisobanuro birambuye

Ifu ya Terbinafine isanzwe igaragara Ifu yera ya kristaline. Ifu ifite uburyo bworoshye kandi bumwe, kandi muri rusange ntabwo ari impumuro nziza. Igikorwa nyamukuru cyifu ya terbinafine ni nkumuti urwanya antifungal. Ikora mukubuza enzyme squalene epoxidase, ingirakamaro kuri biosynthesis ya ergosterol, igice cyingenzi cya the fungal selile membrane.Mu guhungabanya umusaruro wa ergosterol, terbinafine igabanya intege nke za selile, iganisha ku rupfu rwa selile. Ubu buryo bwibikorwa butandukanya terbinafine nindi miti igabanya ubukana kandi ikagira uruhare mubikorwa byayo kurwanya ibihumyo byinshi, harimo dermatofitike, ibumba. , hamwe numusemburo runaka. Ifu ya Terbinafine irashobora gushonga mumashanyarazi kama kandi ikagaragaza ituze mugihe gikwiye.

Ifu ya Terbinafine ifite porogaramu zitandukanye murwego rwa farumasi nubuzima:

1.Imiti ya farumasi: Ifu ya Terbinafine ikora nkibikoresho bya farumasi ikora (API) mugukora imiti itandukanye ya dosiye, harimo amavuta, geles, amavuta, hamwe nibisubizo byibanze.Iyo byinjijwe muribi bisobanuro, terbinafine itanga uburyo bwibanze kandi bugamije kuvura Indwara ya fungal yuruhu, nkibirenge byumukinnyi (tinea pedis), jock itch (tinea cruris), na ringworm (tinea corporis) .Ibicuruzwa byingenzi bikoreshwa muburyo bwuruhu rwanduye, bigatuma terbinafine yinjira aho yanduye kandi igakora ingaruka za antifungal.

2.Guhuza ibicuruzwa: Ifu ya Terbinafine irashobora gukoreshwa muguhuza farumasi hamwe nabashinzwe ubuvuzi kugirango bategure imiti yabugenewe ijyanye nibyifuzo by’abarwayi ku giti cyabo.Ibicuruzwa bivanze bishobora kuba birimo amavuta yihariye, ifu, cyangwa ibisubizo byo kuvura indwara zandurira mu turere aho Irashobora gusaba imiterere idasanzwe, nkumutwe, imisumari, cyangwa ururenda.

3.Ubushakashatsi n'Iterambere: Imiterere itandukanye y'ifu ya terbinafine ituma iba ikintu cy'ingenzi mu bushakashatsi mu bya farumasi no mu iterambere. Abahanga mu bya siyansi n'abashakashatsi barashobora gukoresha ifu ya terbinafine mu gutegura no kugerageza uburyo bushya bwo gutanga imiti, kuzamura ituze na bioavailable ya formulaire ihari, cyangwa gushakisha Ubuvuzi bushya bwo kuvura mubijyanye na farumasi ya antifungal.Ubuvuzi bwamatungo: Ifu ya Terbinafine irashobora kandi kubona imiti mubuvuzi bwamatungo kugirango ivure indwara zandurira mu nyamaswa, harimo dermatophytose nizindi ndwara zuruhu.

4.Ubuvuzi bwamatungo, nka cream cyangwa ifu, birashobora gutegurwa ukoresheje ifu ya terbinafine kugirango ukemure indwara zandurira mu nyamaswa hamwe n’amatungo.

Muri make, ifu ya terbinafine ni ibintu byinshi kandi bikomeye birwanya antifungal hamwe nibisabwa bitandukanye muburyo bwo gufata imiti, guhuza, ubushakashatsi, nubuvuzi bwamatungo. Nibikorwa byinshi byibasira virusi ziterwa na fungal, hamwe nubushake bwabyo nibiranga umutekano, bituma iba umutungo wingenzi kuri gukemura indwara zandurira mubuzima bwabantu ninyamaswa.