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Flumazenil O se GABAA Receptor Antagonist Filifili ma ana Fa'atonuga Fa'afoma'i

Tau Fa'asinomaga:USD 1-2/g

  • Igoa Oloa Flumazenil
  • CAS Nu. 78755-81-4
  • MF C15H14FN3O3
  • MW 303.288363
  • EINECS 616-650-9
  • Malosi 1.39
  • Liu liusuavai 201-203 ℃
Faafesootai matou
fa'amatalaga o oloa

Fa'amatalaga Auiliili

Flumazenil, e taʻua foi o le flumazepil poʻo le igoa ole igoa Ro 15-1788, o se GABAA faʻafeiloaʻi antagonist e mafai ona faʻatinoina e ala i tui, faʻaofiina otic, poʻo intranasally. E galue e pei o se tagata tetee ma vaifofo i benzodiazepines, aemaise lava i tulaga o le soona fai, e ala i le faʻatauvaʻa faʻatauvaʻa. O lenei tusiga o loʻo suʻesuʻeina faʻamanuiaga faʻapitoa, faʻaaogaina e fai ma vaifofo, ma faʻaogaina faʻaogaina ole flumazenil i tulaga faʻafomaʻi eseese.

I. Mechanism of Action:
A. Filifiliga GABAA fa'afeagai tali
B. Taofi fa'atauva i le nofoaga e iloa ai le benzodiazepine
C. Fa'aliliuina a'afiaga o le benzodiazepine

II. Vaitafe mo Benzodiazepine ova le inumaga:
A. Taua o le fa'atauva'a fa'agata i tulaga fa'atupu fa'ama'i
B. Fa'amanuiaga o le flumazenil i le fa'aliliuina o le fa'amalie tele
C. Fa'alavelave ma a'afiaga e feso'ota'i ma le fa'aogaina o le tausiga
D. Mafaufauga mo le tele o tui ma le mata'ituina lelei

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III. Talosaga pe a uma le taotoga:

A. Fa'aliliuina o a'afiaga fa'afilemu o benzodiazepines pe a uma le taotoga

B. Tulaga tutusa ma le fa'aogaina o le naloxone i le suiga ole opioid

C. Mata'ituina e le foma'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i fa'ama'i ma iloiloga pe a mae'a taotoga


IV. Togafitiga o mea e le o Benzodiazepine Hypnotic Overdoses:

A. Ole aoga ole flumazenil ile togafitia ole zolpidem, zaleplon, ma le zopiclone overdoses


V. Talosaga e ono mafai i le Hypersomnia ma A'afiaga o le Gastrointestinal:

A. Fa'aitiitia le tele o le moe ile ao ile hypersomnia muamua

B. Fa'aitiitia a'afiaga o le manava e mafua mai togafitiga o le kanesa

C. Puipuiga o sela o le intestinal i le taimi o le chemotherapy ma le togafitiga fa'avevela


VI. Taua ole Paleni ole GABAA Receptor Inhibition:

A. Puipuia o sela o le intestinal mai le faaleagaina o DNA i le taimi o le leitio

B. Fa'amautinoa e le fa'aletonu le fasiotia o sela o le kanesa



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O le Flumazenil, o le GABAA e fa'afeagai ma le fa'afeagai, e avea o se vaifofo taua i mataupu fa'aletonu o le benzodiazepine, e ofoina atu le fa'atauva'a fa'atauva'a ma le fa'afoliga o a'afiaga fa'afilemu. O ana talosaga e faʻalautele atu i le faʻaaogaina o le taotoga, togafitiga o le le benzodiazepine hypnotic overdoses, ma aoga aoga i le hypersomnia ma aʻafiaga o le manava. O le mataʻituina ma le faʻaeteete o tulaga lamatia e manaʻomia pe a tuʻuina atu le flumazenil, aemaise lava ile tausiga faʻapitoa ma le faʻasologa o taotoga. E mana'omia nisi su'esu'ega e su'esu'e ai lona malosi atoatoa i le puipuia o sela o le intestinal i le taimi o togafitiga o le kanesa a'o fa'atumauina le malosi e fasiotia ai sela o le kanesa.

Fa'amatalaga

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