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Dexamethasone Powder Dexamethasone Raw Materials Dexamethasone CAS 50-02-2
Tsanangudzo Yakadzama
Dexamethasone iupfu chena kana chena, isinganhuhwi. Inonyungudika zvishoma mumethanol, ethanol, acetone, kana dioxane, inonyungudika zvishoma muchloroform, inonyungudika zvishoma muether, uye isinganyungudike mumvura.
Dexamethasone,inozivikanwawo seFlamethasone,flumeprednisolone,desamethasone,iri glucocorticoid hormone.Mazita ayo anosanganisira hydrocodesone,prednisone zvichingodaro,magumisiro ayo emishonga anonyanya kudzivirira kupisa,anti-toxin,anti-allergy,anti-rheumatism,kushandiswa kwekliniki zvakawanda zvakafara.
1.Anti-inflammatory effect:Dexamethasone inogona kuderedza uye kudzivirira mhinduro yetishu pakuzvimba, nokudaro kuderedza kuratidzwa kwekuputika.Mahomoni anodzivisa kuungana kwemasero ekuputika, kusanganisira macrophages uye leukocytes, panzvimbo dzekuputika uye inhibit phagocytosis, kusunungurwa kwe lysosomal. ma enzymes, uye synthesis uye kuburitswa kwemakemikari anomiririra kuzvimba.
2.Immunosuppressive effects:kusanganisira kudzivirira kana kuvharidzira masero-mediated immune responses,kunonoka kusawirirana,kuderedza nhamba yeT lymphocytes,monocytes,uye eosinophils, uye kuderedza kukwanisa kusunga kwema immunoglobulins kune cell surface receptors.,uye inhibits synthesis uye kusunungurwa ye interleukins, nokudaro kuderedza kushandurwa kweT lymphocytes kuva lymphoblasts uye kuderedza kuwedzera kwemhinduro dzekutanga dzekudzivirira zvirwere.Inogona kuderedza kudarika kwezvirwere zvekudzivirira zvirwere kuburikidza nechepasi membrane uye kuderedza kuwanda kwezvikamu zvinopindirana uye immunoglobulins.
Application
Application
1.Inogona kufadza adenylate cyclase, inhibit phosphodiesterase, kuwedzera cAMP mazinga, nokudaro kuwedzera kunzwisiswa kwebronchial beta receptors kune adrenergic zvinodhaka uye theophylline, uye zvisina kunanga kushandisa bronchial antispasmodic effects.Uye nekushandisa anti-inflammatory uye anti-allergic effects. bronchospasm, kuderedza kuzara kwebronchi uye edema, uye kuderedza kubuda kwemachuru.
2.Inoshandiswa kurapa allergic dermatitis, zvinodhaka-induced dermatitis (drug eruption), serum disease, rhinitis, drug reaction, urticaria, allergic purpura, nezvimwewo.
3.Kuvhundutsa:Inogona kushandiswa sekubatsira kwekurapa septic shock,anaphylactic shock uye cardiogenic shock inokonzerwa neacute myocardial infarction kana myocardial conduction block.
4.Toxic zvirwere:Inogona kubvisa zviratidzo zvechepfu inokonzerwa nehutachiona nehutachiona, uye ine yakanaka antipyretic effect.
5.Ulcerative colitis:Inoshandiswa pamwe chete neXilei Powder, nezvimwewo senema yekuchengetedza, inogona kuderedza zviratidzo.
6.Kubatsira mukuongororwa kwe hypercortisolism: Kuita dexamethasone kudzvinyirira test kunogona kubatsira nekuongororwa kwechirwere ichi.
7.Zvirwere zvakasiyana-siyana zvinopisa zvakadai se enteritis, tuberculous meningitis, uveitis, thyroiditis, tuberculosis, trichinellosis, allergic otitis externa, infectious otitis externa, nezvimwewo.
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