Eledoisin Acetate, nhengo yemhuri ye tachykinin, iri peptide inoshanda ine zvakasiyana-siyana zvehupenyu. Inoshanda seine simba vasodilator uye secretagogue, ichiita zviito zvayo pamhasuru dzakatsetseka. Eledoisin Acetate inonyanya kuratidza yakasimba angiotensin II vasoconstriction uye inowedzera BP. Nzira yaro inosanganisira arteriolar smooth muscle contraction, kuwedzera kweperipheral resistance, kusunungurwa kweadrenal aldosterone inotungamira mukuchengetwa kwesodium uye kuwedzerwa kweropa, kugovera zvakananga kune renal tubular sodium uye mvura reabsorption, uye kukurudzira kwekunzwira tsitsi kwevasoconstrictor muuropi, zvichiita kuti kuwedzerwa kweropa vascular. resistance.
Eledoisin Acetate zvakare ine antihypertensive zvimiro. Iyo inozadzisa izvi nekuvhara nzira dzecalcium, kunyanya iyo L-mhando calcium chiteshi mu coronary uye peripheral vascular smooth muscle cells. Nekusarudza kurambidza kupinda kwe calcium ions mumasero, eledoisin inozorodza vascular smooth muscle masero, zvichiita kuti tsinga yeropa iwedzere, kuderedza peripheral resistance, uye pakupedzisira kuderera kweropa.
Pamusoro peiyo antihypertensive mhedzisiro, eledoisin inopa cardioprotective mabhenefiti. Nokuderedza mutoro uri pamwoyo uye kuderedza kushandiswa kweokisijeni yemwoyo, inobatsira kuvandudza kuyerera kweropa, kuwedzera myocardial oxygen supply, uye kuderedza zviratidzo zveangina pectoris.Eledoisin inowanzoshandiswa kurapa chirwere chepamusoro kana chechipiri cheBP. Inogona kushandiswa yoga kana kusanganiswa nemimwe mishonga yeantihypertensive kuti inyatso kudzora kukwira kweropa. Stable Angina Pectoris: Varwere vane angina pectoris yakagadzikana inokonzerwa nechirwere chemwoyo inogona kubatsirwa nekurapa eledoisin. Inobatsira kuderedza zviratidzo zvakadai sekurwadziwa kwechipfuva uye kurwadziwa kwechipfuva, kupa zororo nekuvandudza hutano hwemwoyo.Muzviitiko zveacute coronary syndrome, eledoisin inogona kuonekwa sekuvandudza mamiriro emwoyo wemurwere, kupa rubatsiro uye zvinogona kuderedza dambudziko rematambudziko.
Eledoisin Acetate, peptide yakasiyana-siyana, inoratidza zvakasiyana-siyana zvinokonzerwa nehupenyu, kusanganisira vasodilation, secretagogue basa, uye modulation yemhasuru dzakatsetseka. Iro antihypertensive properties, pamwe chete ne cardioprotective madhara, inoita kuti ive mishonga inokosha yekugadzirisa hypertension uye yakagadzikana angina pectoris. Mune zvimwe zviitiko zvakadai seangina isina kugadzikana uye mamwe mamiriro ane hukama, eledoisin inogonawo kuita basa mukuvandudza hutano hwemwoyo uye zviratidzo. Iine nzira dzayo dzakasiyana-siyana uye kugona kwekurapa, eledoisin Acetate inobata chivimbiso sechisarudzo chekurapa kune akasiyana moyo mamiriro.
