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Leuprorelin Hormone Therapy yeProstate uye Gomarara reMazamu
Leuprorelin Hormone Therapy yeProstate uye Gomarara reMazamu
Leuprorelin Hormone Therapy yeProstate uye Gomarara reMazamu

Leuprorelin Hormone Therapy yeProstate uye Gomarara reMazamu

Reference mutengo: USD 30-100

  • Product name Leuprorelin
  • CAS Nha. 53714-56-0
  • Density 1.44
  • Melting point 150-155°C
  • Boiling point 1720.5°C pa760 mmHg
  • MF C59H84N16O12
  • MW 1269.473
  • Refractive index 1.681
  • Flash point 994.3°C
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product details

Tsanangudzo Yakadzama

Leuprorelin, inozivikanwawo seLupron kana Prostap, ihomoni therapy inoshandiswa mukurapa prostate negomarara rezamu. Ndeyekirasi yemishonga inonzi gonadotropin-releasing hormone (GnRH) agonists. Muchinyorwa chino, tichatarisa nezvekushandiswa kwayo muprostate uye kurapwa gomarara rezamu.

Prostate Cancer Kurapa:
Leuprorelin inowanzoshandiswa kurapa gomarara reprostate. Inoshanda nekudzikisa chiyero che testosterone chinogadzirwa nemachende. Masero egomarara reprostate anotsamira pakukura kwe testosterone, saka kudzikisira mazinga ayo kunogona kuderedza gomarara kana kuderedza kukura kwayo. Kutungamirirwa kweleuprorelin kunobatsira kugadzirisa zviratidzo zvine chokuita nekenza yeprostate yepamusoro uye inovandudza hupenyu hwemurwere.

Kurapa gomarara rezamu:
Leuprorelin inoshandiswawo mukurapa mamwe marudzi egomarara rezamu. Inonyanya kushandiswa mumamiriro ezvinhu apo masero emukenza ane estrogen receptors (ER positive) uye murwere haana kupfuura nekuenda kumwedzi. Leuprorelin inoderedza chiyero cheesrogen mumuviri nekudzvinyirira kugadzirwa kwayo mumaovari. Izvi zvakakosha nekuti huwandu hweestrogen hunogona kukurudzira kukura kwemasero egomarara rezamu. Leuprorelin inogona kupihwa yega kana musanganiswa nemamwe mahormone marapirwo ekugadzirisa zvinobudirira kenza yemazamu.


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Central Precocious Puberty:

Leuprorelin jekiseni, rinozivikanwa seLupron Depot-PED, rinoshandiswa muvana vane makore maviri uye kupfuura kurapa central precocious puberty (CPP). CPP imamiriro ekuti vasikana (kazhinji vari vadiki pane makore masere) nevakomana (kazhinji vari vadiki pane makore 9 ezera) vanopinda mukuyaruka nguva isati yakwana. Leuprorelin inobatsira kudzora nguva yekuyaruka nekudzikisira kukurumidza kukura kwepfupa uye kukura kwehunhu hwepabonde hune chekuita neCPP.


Zvimwe Zvishandiso Zvekiriniki:

Leuprorelin jekiseni, rinozivikanwawo seLupron Depot, rinoshandiswa mukurapa endometriosis uye anemia inokonzerwa neuterine fibroids. Inoshanda nekudzikisira mazinga emamwe mahomoni mumuviri, ichipa zororo kubva kune zviratidzo zvakaita sekurwadziwa, kurema kana kusaenda kumwedzi, uye anemia. Pamusoro pezvo, leuprorelin inogona kushandiswa senge yekurapa isati yaitwa endometrial resection, sezvo ichitetepa endometrium, inoderedza edema, uye kufambisa nzira yekuvhiya.


Pharmacokinetics:
Leuprorelin acetate haishande kana ichitorwa nemuromo uye panzvimbo pacho inopihwa kuburikidza ne subcutaneous kana intramuscular jekiseni. Kutevera jekiseni rimwechete re subcutaneous re 3.75 mg, peak plasma concentration inosvika mukati me1 kusvika kumazuva maviri, nemazinga e1 kusvika 2 ng / ml. Mukurapa kenza yeprostate, jekiseni rezasi re 3.75 mg rinopiwa mavhiki ose e4 kwehuwandu hwemajekiseni e3 kuti uwane kugadzikana-mamiriro e plasma ye 0.1 kusvika 1 ng / ml. Leuprorelin inogadziriswa kuita zvigadzirwa zvina zvinoshatisa mumuviri uye inoburitswa zvakanyanya kuburikidza neitsvo.

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Mhedziso:
Leuprorelin, GnRH agonist, yakakosha kurapa kwehomoni inoshandiswa mukurapa kweprostate negomarara rezamu, pamwe nepakati precocious pakuyaruka, endometriosis, uye anemia inokonzerwa neuterine fibroids. Nekudzikisa testosterone kana estrogen mazinga, leuprorelin inobatsira kudzora kukura uye zviratidzo zvine chekuita nemamiriro aya. Kutungamirirwa kweLeuprorelin kunoda kutarisirwa kwechiremba uye kuongororwa nguva dzose kuti ive nechokwadi chekushanda kwayo uye kugadzirisa chero zvingangoitika.

Rangarira kutibata nesu kune akadzama ekurongedza uye ekutumira mafomu, isu tinopa nyanzvi OEM / ODM kugadzirisa masevhisi.

Tsanangudzo

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