Dexamethasone Powder Dexamethasone Raw Materials Dexamethasone CAS 50-02-2

Lebitso la Sehlahiswa Dexamethasone
Ponahalo Phofo ea kristale e tšoeu kapa e batlang e le tšoeu
Nomoro ea CAS. 50-02-2
Foromo ea Lik'hemik'hale C22H29FO5
Boima ba molek'hule 392.46
Sebaka se qhibilihang 262-264 °C(lit.)
Ntho e belang 568.2oC ho 760 mmHg
Botenya 76 ° (C=1, Dioxane) Potoloho e khethehileng 75° (c=1, dioxane)

Iteanye le rona

lintlha tsa sehlahisoa

Tlhaloso e Felletseng

Dexamethasone ke phofo e soeufetseng kapa e batlang e le tšoeu, ha e na monko. E qhibiliha hanyenyane ka methanol, ethanol, acetone, kapa dioxane, e qhibiliha hanyenyane ka chloroform, e qhibiliha hanyenyane haholo ka ether, 'me e batla e sa qhibilihe ka metsing.

Dexamethasone, eo hape e tsejoang e le Flamethasone,flumeprednisolone,desamethasone,ke hormone ea glucocorticoid.Metsoako ea eona e kenyelletsa hydrocodesone,prednisone joalo-joalo, litlamorao tsa eona tsa pharmacological haholo-holo li khahlanong le ho ruruha,anti-toxin,anti-allergy,anti-rheumatism,tšebeliso ea bongaka ke haholo ka bophara.

1.Anti-inflammatory effect: Dexamethasone e ka fokotsa le ho thibela karabelo ea lisele ho ruruha, ka tsela eo, ea fokotsa ponahalo ea ho ruruha. Li-hormone li thibela ho bokellana ha lisele tsa ho ruruha, ho akarelletsa le macrophages le leukocyte, libakeng tsa ho ruruha le ho thibela phagocytosis, ho lokolloa ha lysosomal. li-enzyme, le ho qaptjoa le ho lokolloa ha li-mediator tsa lik'hemik'hale tsa ho ruruha.

2. Liphello tsa Immunosuppressive: ho kenyelletsa ho thibela kapa ho thibela likarabelo tsa 'mele oa ho itšireletsa mafung, ho lieha ho arabela, ho fokotsa palo ea T lymphocyte, monocyte, le eosinophils, le ho fokotsa matla a tlamang a li-immunoglobulins ho li-receptor tsa lisele. ea li-interleukins, kahoo e fokotsa phetoho ea li-lymphocyte tsa T ho li-lymphoblasts le ho fokotsa ho atolosoa ha likarabo tsa mantlha tsa 'mele oa ho itšireletsa mafung.E ka fokotsa ho feta ha metsoako ea 'mele ea ho itšireletsa mafung ka lera le ka tlaase le ho fokotsa khatello ea likarolo tse tlatsetsang le li-immunoglobulins.

Kopo

1.E ka hlasimolla adenylate cyclase, inhibit phosphodiesterase, eketsa maemo a cAMP, kahoo ea eketsa kutloelo-bohloko ea li-receptor tsa bronchial beta ho lithethefatsi tsa adrenergic le theophylline, 'me ka tsela e sa tobang ea fana ka litlamorao tsa bronchial antispasmodic. bronchospasm, fokotsa tšubuhlellano ea bronchial le edema, le ho fokotsa secretion ea mamina.

2.E sebelisoa ho alafa mafu a allergic: joalo ka allergic dermatitis, dermatitis e bakoang ke lithethefatsi (ho phatloha ha lithethefatsi), serum disease, rhinitis, ho itšoara ka lithethefatsi, urticaria, allergic purpura, joalo-joalo.

3.Shock:E ka sebelisoa e le kalafo e thusang bakeng sa septic shock, anaphylactic shock le cardiogenic shock e bakoang ke acute myocardial infarction kapa myocardial conduction block.

4.Mafu a chefo: E ka imolla matšoao a chefo e bakoang ke tšoaetso ea baktheria le kokoana-hloko, 'me e na le phello e ntle ea antipyretic.

5.Ulcerative colitis: E sebelisoa hammoho le Xilei Powder, joalo-joalo e le enema ea ho boloka, e ka imolla matšoao.

6. Thusa ho hlahloba hypercortisolism: Ho etsa tlhahlobo ea khatello ea dexamethasone ho ka thusa ho fumana lefu lena.

7.Mafu a fapaneng a ho ruruha a kang enteritis, lefuba la meningitis, uveitis, thyroiditis, lefuba, trichinellosis, allergic otitis externa, infectious otitis externa, joalo-joalo.