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Flumazenil Mohanyetsi oa Moamoheli oa GABAA ea Khethiloeng le Likopo tsa eona tsa Phekolo

Theko ea Litšupiso:USD 1-2/g

  • Lebitso la Sehlahiswa Flumazenil
  • Nomoro ea CAS. 78755-81-4
  • MF Setšoantšo sa C15H14FN3O3
  • MW 303.288363
  • EINECS 616-650-9
  • Botenya 1.39
  • Sebaka se qhibilihang 201-203 ℃
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lintlha tsa sehlahisoa

Tlhaloso e Felletseng

Flumazenil, eo hape e tsejoang e le flumazepil kapa lebitso la khoutu Ro 15-1788, ke mohanyetsi ea khethiloeng oa GABAA ea ka tsamaisoang ka ente, ho kenya otic, kapa intranasally. E sebetsa joalo ka mohanyetsi le antidote ho benzodiazepines, haholo maemong a overdose, ka thibelo ea tlholisano. Sengoliloeng sena se hlahloba melemo ea kalafo, ts'ebeliso e le pheko, le ts'ebeliso e ka bang teng ea flumazenil maemong a fapaneng a bongaka.

I. Mokhoa oa Ts'ebetso:
A. Mohanyetsi oa moamoheli ea khethiloeng oa GABAA
B. Thibelo ea tlhōlisano sebakeng sa ho tsebahatsa benzodiazepine
C. Phetoho ea liphello tsa benzodiazepine

II. Antidote bakeng sa Overdose ea Benzodiazepine:
A. Bohlokoa ba ho thibela tlhōlisano maemong a overdose
B. Melemo ea flumazenil ho khutlisa sedation e feteletseng
C. Mathata le likotsi tse amanang le tšebeliso ea tlhokomelo e matla
D. Lintlha tse mabapi le ho noa hangata le ho beha leihlo ka hloko

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III. Kopo ea Kamora ho buuoa:

A. Phetoho ea liphello tsa sedative tsa benzodiazepines ka mor'a ho buuoa

B. Ho tšoana le tšebeliso ea naloxone ho fetola opioid

C. Tlhokomelo ea ngaka e robatsang ka lithethefatsi le ho nahana ka mor'a ho buuoa


IV. Kalafo ea Non-Benzodiazepine Hypnotic Overdoses:

A. Ho sebetsa hantle ha flumazenil ho alafa zolpidem, zaleplon, le overdose ea zopiclone.


V. Lits'ebetso tse ka 'nang tsa E-ba teng ho Hypersomnia le Litlamorao tsa Gastrointestinal:

A. Phokotso ea boroko bo feteletseng ba motšehare ho hypersomnias ea mantlha

B. Phokotso ea litla-morao tsa mala a bakoang ke liphekolo tsa mofets'e

C. Tšireletso ea lisele tsa stem tsa mala nakong ea chemotherapy le phekolo ea mahlaseli


VI. Bohlokoa ba ho leka-lekanya GABAA Receptor Inhibition:

A. Ho sireletsa lisele tsa mala ho tsoa tšenyo ea DNA nakong ea radiotherapy

B. Ho netefatsa hore ho bolaoa ha lisele tsa mofets'e ha ho sekisetsoe



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Flumazenil, mohanyetsi ea khethiloeng oa GABAA receptor, e sebetsa e le pheko ea bohlokoa maemong a overdose ea benzodiazepine, e fanang ka thibelo ea tlholisano le ho khutlisa litlamorao tsa sedative. Ts'ebeliso ea eona e atoloha ts'ebelisong ea kamora ho buuoa, kalafo ea li-non-benzodiazepine hypnotic overdoses, le melemo e ka bang teng ho hypersomnia le litla-morao tsa mala. Tlhokomelo e hlokolosi le ho nahanela likotsi li bohlokoa ha u fana ka flumazenil, haholo-holo maemong a tlhokomelo e matla le ka mor'a ho buuoa. Ho hlokahala lipatlisiso tse ling ho hlahloba bokhoni ba eona bo felletseng ba ho sireletsa lisele tsa mala nakong ea kalafo ea mofets'e ha ho ntse ho bolokoa katleho ea ho bolaea lisele tsa mofetše.

Tlhaloso

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