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Leuprorelin Hormone Therapy bakeng sa Prostate le Kankere ea Matsoele
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Leuprorelin Hormone Therapy bakeng sa Prostate le Kankere ea Matsoele

Leuprorelin Hormone Therapy bakeng sa Prostate le Kankere ea Matsoele

Theko ea litšupiso: USD 30-100

  • Lebitso la sehlahisoa Leuprorelin
  • Nomoro ea CAS. 53714-56-0
  • Botenya 1.44
  • Sebaka se qhibilihang 150-155°C
  • Ntho e belang 1720.5°C ho 760 mmHg
  • MF Setšoantšo sa C59H84N16O12
  • MW 1269.473
  • Lenane la refractive 1.681
  • flash point 994.3°C
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lintlha tsa sehlahisoa

Tlhaloso e Felletseng

Leuprorelin, e tsejoang hape e le Lupron kapa Prostap, ke phekolo ea li-hormone e sebelisoang ho phekola tšoelesa ea senya le mofetše oa matsoele. Ke ea sehlopha sa meriana e bitsoang gonadotropin-releasing hormone (GnRH) agonists. Moqoqong ona, re tla shebana haholo le tšebeliso ea eona kalafong ea mofetše oa tšoelesa ea senya le mofetše oa matsoele.

Kalafo ea Kankere ea Prostate:
Leuprorelin hangata e sebelisoa ho phekola mofetše oa tšoelesa ea senya. E sebetsa ka ho theola boemo ba testosterone e hlahisoang ke li-testicles. Lisele tsa kankere ea tšoelesa ea senya li itšetlehile ka testosterone bakeng sa khōlo, kahoo ho fokotsa maemo a eona ho ka fokotsa mofetše kapa ho liehisa khōlo ea eona. Tsamaiso ea leuprorelin e thusa ho laola matšoao a amanang le mofetše oa prostate e tsoetseng pele le ho ntlafatsa boleng ba bophelo ba mokuli.

Kalafo ea Kankere ea Matsoele:
Leuprorelin e boetse e sebelisoa ho phekola mefuta e itseng ea mofetše oa matsoele. E sebelisoa ka ho khetheha maemong ao lisele tsa kankere li nang le li-receptor tsa estrogen (ER positive) 'me mokuli a e-s'o fete nakong ea ho ilela khoeli. Leuprorelin e fokotsa boemo ba estrogen ’meleng ka ho hatella tlhahiso ea eona ka mae a bomme. Sena ke sa bohlokoa hobane litekanyetso tse phahameng tsa estrogen li ka khothalletsa ho hōla ha lisele tsa kankere ea matsoele. Leuprorelin e ka tsamaisoa e le mong kapa e kopane le litlhare tse ling tsa li-hormone ho laola mofetše oa matsoele ka nepo.


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Bochaba ba Bohareng ba Bokhachane:

Ente ea Leuprorelin, e tsejoang ka hore ke Lupron Depot-PED, e sebelisoa ho bana ba lilemo tse 2 ho ea holimo ho alafa boroetsana ba precocious (CPP). CPP ke boemo boo ho bona banana (hangata ba ka tlase ho lilemo tse 8) le bashanyana (hangata ba ka tlase ho lilemo tse 9) ba kenang bohlankaneng pele ho nako. Leuprorelin e thusa ho laola nako ea ho kena bohlankaneng ka ho liehisa ho hōla ha masapo ka potlako le nts'etsopele ea litšobotsi tsa thobalano tse amanang le CPP.


Lisebelisoa tse ling tsa Clinical:

Ente ea Leuprorelin, e tsejoang hape e le Lupron Depot, e sebelisoa ho phekola endometriosis le phokolo ea mali e bakoang ke uterine fibroids. E sebetsa ka ho fokotsa maemo a lihomone tse itseng 'meleng, ho fana ka phomolo matšoao a kang bohloko, ho ilela khoeli ho boima kapa ho sa tloaelehang, le phokolo ea mali. Ho feta moo, leuprorelin e ka sebelisoa e le kalafo ea pele ho kalafo pele ho ts'ebetso ea endometrial, kaha e fokotsa endometrium, e fokotsa edema, hape e thusa ho buoa.


Pharmacokinetics:
Leuprorelin acetate ha e sebetse ha e nkoa ka molomo mme ho e-na le hoo e tsamaisoa ka ente ea subcutaneous kapa intramuscular. Ka mor'a ente e le 'ngoe ea subcutaneous ea 3.75 mg, tlhōrō ea mahloriso a plasma e fihlella ka hare ho matsatsi a 1 ho isa ho a 2, ka litekanyetso tsa 1 ho 2 ng / ml. Ka phekolo ea kankere ea tšoelesa ea senya, ente ea subcutaneous ea 3.75 mg e fanoa libeke tse ling le tse ling tsa 4 bakeng sa kakaretso ea liente tsa 3 ho finyella maemo a tsitsitseng a plasma a 0.1 ho 1 ng / ml. Leuprorelin e kenngoa ka har'a lihlahisoa tse 'nè tse senyang' meleng 'me e ntšoa haholo-holo ka liphio.

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Qetello:
Leuprorelin, GnRH agonist, ke phekolo ea bohlokoa ea li-hormone e sebelisoang ho alafa tšoelesa ea senya le mofetše oa matsoele, hammoho le boroetsana bo sa lebelloang, endometriosis le phokolo ea mali e bakoang ke uterine fibroids. Ka ho fokotsa maemo a testosterone kapa estrogen, leuprorelin e thusa ho laola kholo le matšoao a amanang le maemo ana. Tsamaiso ea leuprorelin e hloka tlhokomelo ea bongaka le tlhokomelo ea kamehla ho netefatsa katleho ea eona le ho laola litla-morao leha e le life tse ka bang teng.

Hopola ho ikopanya le rona bakeng sa ho paka ka botlalo le liforomo tsa thomello, re tla fana ka lits'ebeletso tsa profeshenale tsa OEM/ODM.

Tlhaloso

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