I-Dexamethasone Powder I-Dexamethasone Izixhobo ezikrwada I-Dexamethasone CAS 50-02-2
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Idexamethasone ngumgubo omhlophe okanye ophantse wamhlophe oyikristale, awunavumba. Inyibilika kancinane kwimethanol, ethanol, iacetone, okanye idioxane, inyibilika kancinane kwichloroform, inyibilika kancinane kwi-ether, kwaye ayinyibiliki namanzi.
IDexamethasone, ekwabizwa ngokuba yiFlamethasone, flumeprednisolone,desamethasone, yiglucocorticoid hormone.Izinto eziphuma kuyo ziquka ihydrocodesone,prednisone njalo njalo,iziphumo zayo zepharmacological ikakhulu zichasene nokudumba,anti-toxin,anti-allergy,anti-rheumatism,ukusetyenziswa kwezonyango ngokubanzi.
I-1.I-Anti-inflammatory effect: I-Dexamethasone inokunciphisa kwaye ithintele impendulo yezicubu ekuvukeni, ngaloo ndlela inciphisa ukubonakaliswa kokuvuvukala.I-Hormones inqanda ukuqokelelwa kweeseli ezivuthayo, kubandakanywa i-macrophages kunye ne-leukocytes, kwiindawo zokuvuvukala kunye nokuvimbela i-phagocytosis, ukukhululwa kwe-lysosomal. ii-enzymes, kunye nokuhlanganiswa kunye nokukhululwa kwabalamli beekhemikhali zokudumba.
2.Iziphumo ze-Immunosuppressive:kubandakanya ukuthintela okanye ukuthintela ukuphendula kwe-immune-immune, ukulibaziseka ukuphendula, ukunciphisa inani le-T lymphocytes, i-monocytes, kunye ne-eosinophils, kunye nokunciphisa amandla okubopha i-immunoglobulins kwi-cell cell receptors., kwaye inhibits synthesis kunye nokukhulula ye-interleukins, ngaloo ndlela inciphisa ukuguqulwa kwe-T lymphocytes kwi-lymphoblasts kunye nokunciphisa ukwandiswa kweempendulo ze-immune eziphambili.Inokunciphisa ukuhamba kwe-immune complexes ngokusebenzisa i-membrane yesiseko kunye nokunciphisa ukuxinwa kwezinto ezincedisayo kunye ne-immunoglobulins.
Isicelo
Isicelo
I-1.Inokuvuyisa i-adenylate cyclase, inhibit phosphodiesterase, ukwandisa amanqanaba e-cAMP, ngaloo ndlela ikhulise uvakalelo lwe-beta receptors ye-bronchial kwiziyobisi ze-adrenergic kunye ne-theophylline, kwaye isebenzise ngokungangqalanga imiphumo ye-bronchial antispasmodic.Kwaye ngokusebenzisa i-anti-inflammatory and anti-allergic effects. i-bronchospasm, ukunciphisa ukuxinana kwe-bronchial kunye ne-edema, kunye nokunciphisa ukukhutshwa kwe-mucus.
2.Isetyenziselwa ukunyanga izifo: ezifana ne-allergic dermatitis, i-dermatitis-induced dermatitis (ukuqhuma kweziyobisi), ukugula kwe-serum, i-rhinitis, ukusabela kweziyobisi, i-urticaria, i-allergic purpura, njl.
3. Umothuko:Ingasetyenziswa njengonyango oluncedisayo kwi-septic shock, umothuko we-anaphylactic kunye nomothuko we-cardiogenic obangelwa yi-acute myocardial infarction okanye i-myocardial conduction block.
4.Izifo ezinetyhefu:Inokuphelisa iimpawu zetyhefu ezibangelwa lusulelo lwebhaktiriya kunye nentsholongwane, kwaye inesiphumo esihle se-antipyretic.
5.I-ulcerative colitis: Isetyenziswa kunye ne-Xilei Powder, njl.njl njenge-enema yogcino, inokuphelisa iimpawu.
6.Ukuncedisa ekuxilongweni kwe-hypercortisolism:Ukwenza uvavanyo lokunciphisa i-dexamethasone kunokuncedisa ukuxilongwa kwesi sifo.
7.Izifo ezahlukeneyo ezivuthayo ezifana ne-enteritis yendawo, i-meningitis ye-tuberculous, uveitis, i-thyroiditis, isifo sephepha, i-trichinellosis, i-allergic otitis yangaphandle, i-otitis eyosulelayo ngaphandle, njl.
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