I-Estradiol yabasetyhini iSebenzisa i-99% ye-Purity Estradiol Hormone Powder
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I-Estradiol, i-CAS No.57-91-0, i-estrogen esebenzayo ye-biologically kunye noluhlu olubanzi lwezicelo zonyango.Ibonakala njenge-White okanye iphantse i-crystalline powder emhlophe, i-soluble kwi-ethanol, i-acetone kunye ne-alkaline isisombululo samanzi.
Enye yeempawu eziphambili ze-17α-Estradiol yikhono layo lokujongana nokuxhaswa kwe-estrogen eyaneleyo, inkxalabo eqhelekileyo kubasetyhini abafumana i-hypogonadism. Ngokubonelela nge-biologically esebenzayo ye-estrogen, le khompawundi inika isisombululo esijoliswe kuyo sokubuyisela ibhalansi yehomoni kunye nokujongana neempawu ezinxulumene nokusilela kwe-estrogen. Oku kwenza ukuba ibe yongezelelo oluxabisekileyo kwi-arsenal yonyango olukhoyo kule meko, inika ithemba elitsha kwizigulana kunye nababoneleli bezempilo ngokufanayo.
Ukongeza kwindima yayo ekujonganeni nokusilela kwe-estrogen, i-17α-Estradiol ibonise amandla okuthintela i-osteoporosis, imeko ebonakaliswe ngokuncipha kwamathambo kunye nomngcipheko okhulayo wokuphuka. Ngokukhuthaza impilo yamathambo kunye nokuxinana, le khompawundi inamandla okubonelela ngendlela esebenzayo yokulawula i-osteoporosis, ngakumbi kubasetyhini abasemva kokuphuma kokuya esikhathini abasengozini enkulu yale meko. Ngokukwazi kwayo ukuxhasa amandla ethambo kunye nokuthembeka, i-17α-Estradiol ibonisa indlela ethembisayo yokukhuthaza impilo yamathambo exesha elide.
Ngaphandle kwezicelo zayo kwimpilo yabasetyhini, i-17α-Estradiol ibonise isithembiso ekujonganeni ne-leukopenia ebangelwa i-chemotherapy okanye i-radiotherapy ye-tumor ezimbi. Le meko, ebonakala ngokuhla kwenani leeseli ezimhlophe zegazi, inokushiya izigulana zisengozini yosulelo kunye nezinye iingxaki. Ngokwandisa kakhulu inani leeseli ezimhlophe zegazi, i-17α-Estradiol inikezela ngesisombululo esinamandla sokulawula i-leukopenia kunye nokuxhasa amajoni omzimba ngexesha lonyango lomhlaza. Oku kubonisa ukuqhubela phambili okubonakalayo kukhathalelo lwenkxaso olufumanekayo kwizigulana ezinomhlaza, ebonelela ngendlela entsha yokujongana nalo mba ucelomngeni wonyango lomhlaza.
Imiphumo enokubakho ye-17α-Estradiol kwizicwangciso zokutshintshwa kwehomoni kwi-menopause kunye nokunyangwa kweengxaki ze-neurodeergenerative ezifana nesifo se-Alzheimer kunye ne-ischemic stroke ziphawuleka ngokukodwa. Nge-receptor yayo ekhethiweyo, i-ER-X, kunye nendima yayo kwimisebenzi ye-autocrine / paracrine ekuphuhliseni kunye nobuchopho obudala, i-17α-Estradiol inesithembiso sokujongana noluhlu lweemeko ezineempembelelo ezibalulekileyo kubomi bezigulane. Njengoko uphando kule ndawo luqhubeka nokuguquka, amandla okuba i-17α-Estradiol inike iindlela ezintsha zonyango kule meko enzima yinto enomdla kwixesha elizayo lokunakekelwa kwezempilo.
Ekugqibeleni, i-17α-Estradiol i-compound ibonise iziphumo ezithembisayo kunyango lwe-hypogonadism yabasetyhini, i-osteoporosis, kunye ne-leukopenia ebangelwa i-chemotherapy okanye i-radiotherapy ye-tumor ezimbi. Ngeempembelelo zayo ezinokuthi zenzeke kwizicwangciso zokutshintshwa kwehomoni kwi-menopause kunye nonyango lweengxaki ze-neurodeergenerative ezifana nesifo se-Alzheimer kunye ne-ischemic stroke, i-17α-Estradiol ilungele ukwenza impembelelo ebalulekileyo kwintsimi yempilo yabasetyhini nangaphezulu.
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