I-Telmisartan Ingcono i-antihypertensive Ukukhusela izintso

Ukukhuselwa kwemithambo ye-cardiovascular and cerebral:

I-Telmisartan ibalasele njengeyodwa ichiza elifana ne-sartan elivunywe yi-FDA kwiipropathi zalo zokhuselo lwentliziyo kunye ne-cerebrovascular. Ibonisa ukukwazi ukubuyisela umva i-hypertrophy ye-ventricular yasekhohlo kwaye iyacetyiswa kwizigulane ezine-hypertension ehamba ne-left ventricular hypertrophy, insufficiency cardiac, okanye isifo se-coronary artery. Ukongeza kwiziphumo zayo zokunciphisa uxinzelelo lwegazi, iTelmisartan inciphisa ukonakala kwentliziyo kunye ne-cerebrovascular. Iluncedo kakhulu kubantu abaye bafumana i-stroke okanye i-cardiac infarction.

Ukukhusela umsebenzi wezintso:

Enye inzuzo yeTelmisartan yimpembelelo yayo entle ekusebenzeni kwezintso. Kuba iTelmisartan ifumana i-hepatic metabolism kwaye ikhutshelwa kwi-bile, inefuthe elincinci ekusebenzeni kwezintso. Ngaphezu koko, iTelmisartan ifunyenwe inciphisa iproteinuria, ngaloo ndlela ikhusela ukusebenza kwezintso. Iluncedo ngakumbi kwizigulana ezinoxinzelelo lwegazi kunye neemeko ze-comorbid ezifana ne-nephropathy yesifo sikashukela, i-microalbuminuria, i-proteinuria, okanye i-mild to moderate insuffence renal.

Ukuphucula ukunganyangeki kwe-insulin:

I-Telmisartan ibonise iziphumo ezilungileyo kwimetabolism ye-glucose kunye nokumelana ne-insulin. Olu phawu lwenza ukuba lube lukhetho olufanelekileyo kwizigulane ezine-hypertension kunye nesifo sikashukela, njengoko kunokunceda ukuphucula ukuvakalelwa kwe-insulin kunye nokulawula i-glucose.