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Vasopressin Multifaceted Hormone Regulating Fluid Balance
Vasopressin Multifaceted Hormone Regulating Fluid Balance
Vasopressin Multifaceted Hormone Regulating Fluid Balance
Vasopressin Multifaceted Hormone Regulating Fluid Balance

Vasopressin Multifaceted Hormone Regulating Fluid Balance

Ixabiso leReference:USD 40-100

  • Igama lemveliso Vasopressin
  • Inombolo yeCAS. 11000-17-2
  • Imbonakalo Umgubo oMhlophe weLyophilized
  • MF I-C46H65N13O12S2
  • MW 1056.22
  • EINECS 234-236-2
  • Ukuxinana 1.31g/cm3
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Inkcazo eneenkcukacha

IVasopressin, ekwabizwa ngokuba yi-antidiuretic hormone (ADH), idlala indima ebalulekileyo ekulawuleni i-osmolality yolwelo ngokukhuthaza ukuphinda kufakwe emanzini ezintso. Le hormone ayibangeli iziphumo ze-antidiuretic kuphela kodwa ibonisa iimpawu ze-vasoconstrictive kwaye ichaphazela amalungu ahlukeneyo afana nesisu, i-gallbladder, kunye nesinye. I-Vasopressin isetyenziselwa unyango lwe-uremia ephakathi, i-polyuria emva kokuhlinzwa kwengqondo okanye ukuxhatshazwa kwentloko, ukuphumla kwezihlunu zesisu, kunye nokuncedisa ekulawuleni i-hemorrhage enzima.

I-Vasopressin isebenza njengomlawuli oyintloko we-osmolality yamanzi ngokunyusa ukubuyiswa kwamanzi kwizintso. Ngokwandisa ukunyanzeliswa kweeseli ze-epithelial kwimibhobho yokuqokelela izintso, i-vasopressin ikhuthaza ukubuyiswa kwamanzi, okukhokelela kwisiphumo se-antidiuretic. Ukongezelela, ibonisa iimpawu ze-vasoconstrictive, ezithintela i-vasculature ye-peripheral, kwaye ibangela ukuxinwa kwamathumbu, i-gallbladder, kunye nesinye.


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Kunyango lwe-uremia ephakathi, i-vasopressin isetyenziselwa ukulawula iimpawu ezinxulumene nokunqongophala kwe-pressin, njengezixa ezininzi zomchamo wamanzi kunye nokwanda konxano. Inceda ukubuyisela ibhalansi ye-osmolality yolwelo lomzimba ngokunyusa ukubuyiswa kwamanzi kwi-renal tubular yokuqokelela imibhobho, ekhokelela ekunciphiseni ukuveliswa komchamo kunye nokuxinana kwesodium kumchamo.

IVasopressin ikwasetyenziswa kunyango lokuqala lwe-polyuria emva kotyando lobuchopho okanye ukwenzakala entloko. Ngokulawula ibhalansi yamanzi, i-vasopressin inceda ekunciphiseni ukuveliswa komchamo ngokugqithisileyo kunye nokugcina i-hydration efanelekileyo.

Ngaphaya koko, ivasopressin ifumana ukusetyenziswa ekuphumleni izihlunu zesisu xa amanye amachiza engasebenzi. Ikhono layo lokubangela i-vasoconstriction kunye nokuchaphazela ukunyanzeliswa kwemisipha egudileyo kunika ukukhululeka kwiimeko ezithile apho ukuphumla kwemisipha kuyadingeka.

Kwi-hemorrhage eyingozi ebangelwa zizifo ze-esophagus, i-gastrointestinal tract, kunye nezinye iindlela zokugaya, i-vasopressin ingasetyenziswa njenge-adjunct kunyango. Iimpawu zayo ze-vasoconstrictive zinceda ekunciphiseni ukuphuma kwegazi kunye nokuzinzisa imeko yesigulane.
I-Vasopressin yenziwa phakathi kwi-hypothalamus njenge-cyclic nonapeptide. Ithatha inxaxheba kwi-hypothalamic-pituitary-adrenal axis kwaye ilawula i-pituitary corticotropin secretion ngokunyusa imiphumo ye-corticotropin-releasing factor. Ukongezelela, i-vasopressin isebenza njenge-neurotransmitter, yenza isenzo sayo ngokuzibophelela kwii-receptors ezithile ze-G protein-coupled.

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IVasopressin, ekwabizwa ngokuba yi-antidiuretic hormone, idlala indima ebalulekileyo ekulawuleni ibhalansi yolwelo emzimbeni. Ukukwazi kwayo ukuvuselela ukubuyiswa kwamanzi, i-vasoconstriction, kunye nokuchaphazela izitho ezahlukeneyo kwenza ihomoni eguquguqukayo kunye nezicelo ezininzi zonyango. Ukusuka ekulawulweni kwe-uremia ephakathi kunye ne-polyuria ukuya ekuncedeni ekuphumleni kwemisipha yesisu kunye nokulawula ukopha okukhulu, i-vasopressin ibonisa ukusebenza kwayo kwiimeko ezahlukeneyo zeklinikhi.

Inkcazo

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