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I-Dexamethasone Powder I-Dexamethasone Raw Materials I-Dexamethasone CAS 50-02-2
Incazelo Eningiliziwe
I-Dexamethasone iyimpushana ecwebezelayo emhlophe noma ecishe ibe mhlophe, ayinaphunga. Incibilika kancane ku-methanol, i-ethanol, i-acetone, noma i-dioxane, incibilika kancane ku-chloroform, incibilika kancane ku-ether, futhi ayincibiliki emanzini.
I-Dexamethasone, eyaziwa nangokuthi i-Flamethasone, i-flumeprednisolone, i-desamethasone, iyi-hormone ye-glucocorticoid. Okuphuma kuyo kubalwa i-hydrocodesone, i-prednisone nokunye, imiphumela yayo yezemithi ikakhulukazi i-anti-inflammatory, anti-toxin, anti-allergy, anti-rheumatism, ukusetshenziswa emtholampilo kabanzi.
1.Umphumela wokulwa nokuvuvukala: I-Dexamethasone inganciphisa futhi ivimbele ukuphendula kwezicubu ekuvuvukeni, ngaleyo ndlela inciphise ukubonakaliswa kokuvuvukala.Amahomoni avimbela ukunqwabelana kwamangqamuzana avuthayo, okuhlanganisa ama-macrophage namaleukocyte, ezindaweni zokuvuvukala futhi uvimbele i-phagocytosis, ukukhululwa kwe-lysosomal. ama-enzyme, kanye nokuhlanganiswa nokukhululwa kwabaxhumanisi bamakhemikhali bokuvuvukala.
2.Imiphumela ye-Immunosuppressive: okuhlanganisa ukuvimbela noma ukuvimbela ukuphendula kwamasosha omzimba ahlanganisiwe, ukubambezeleka kokungezwani komzimba, ukunciphisa inani lama-T lymphocyte, ama-monocyte, nama-eosinophils, nokunciphisa ikhono lokubopha ama-immunoglobulins kuma-cell surface receptors., futhi kuvimbela ukuhlanganiswa nokukhulula ama-interleukins, ngaleyo ndlela kunciphisa ukuguqulwa kwe-T lymphocyte ibe yi-lymphoblasts futhi kunciphise ukunwetshwa kwezimpendulo zokuzivikela eziyinhloko.Kunganciphisa ukudlula kwe-immune complexes ngokusebenzisa ulwelwesi olungaphansi futhi kunciphise ukuhlushwa kwezingxenye ezihambisanayo nama-immunoglobulins.
Isicelo
Isicelo
1.Ingajabulisa i-adenylate cyclase, ivimbele i-phosphodiesterase, ikhuphule amazinga e-cAMP, ngaleyo ndlela ikhulise ukuzwela kwama-receptors e-bronchial beta emithini ye-adrenergic ne-theophylline, futhi isebenzise imiphumela ye-bronchial antispasmodic ngokungaqondile. i-bronchospasm, yehlisa ukuminyana kwe-bronchial kanye ne-edema, futhi yehlise ukuphuma kwamafinyila.
2.Isetshenziswa ekwelapheni izifo ezingezwani nomzimba:njenge-allergic dermatitis,i-dermatitis ebangelwa izidakamizwa(ukuqhuma kwezidakamizwa),isifo se-serum,i-rhinitis,ukusabela kwezidakamizwa,i-urticaria,i-allergic purpura, njll.
3.Ukushaqeka:Ingasetshenziswa njengendlela yokwelapha eyisizayo yokushaqeka kwe-septic, ukushaqeka kwe-anaphylactic kanye nokushaqeka kwenhliziyo okubangelwa i-acute myocardial infarction noma i-myocardial conduction block.
4.Izifo ezinobuthi: Ingakhulula izimpawu zobuthi obubangelwa izifo ezibangelwa amagciwane kanye negciwane, futhi inomphumela omuhle we-antipyretic.
5.I-ulcerative colitis: Isetshenziswa kanye ne-Xilei Powder, njll.njenge-enema yokugcinwa, ingadambisa izimpawu.
6.Ukusiza ekuxilongweni kwe-hypercortisolism: Ukwenza ukuhlolwa kokucindezela i-dexamethasone kungasiza ekuxilongeni kwalesi sifo.
7.Izifo ezihlukahlukene ezivuthayo ezifana ne-enteritis yendawo, i-meningitis ye-tuberculous, uveitis, i-thyroiditis, isifo sofuba, i-trichinellosis, i-allergic otitis externa, i-otitis yangaphandle ethathelwanayo, njll.
Ukucaciswa
