0102030405
I-Estradiol Female Sebenzisa i-99% Purity Estradiol Hormone Powder
Incazelo Eningiliziwe
I-Estradiol,i-CAS No.57-91-0, i-estrogen esebenzayo yezinto eziphilayo ezinohlu olubanzi lwezicelo zokwelapha.Ibonakala njenge-White noma cishe i-crystalline powder emhlophe, encibilika ku-ethanol, i-acetone nesisombululo se-alkaline samanzi.
Esinye sezici eziyinhloko ze-17α-Estradiol yikhono layo lokubhekana nokuxhaswa kwe-estrogen okwanele, ukukhathazeka okuvamile kwabesifazane ababhekene ne-hypogonadism. Ngokunikeza uhlobo lwe-estrogen olusebenzayo ngokwezinto eziphilayo, le nhlanganisela inikeza isisombululo esihlosiwe sokubuyisela ibhalansi yamahomoni kanye nokubhekana nezimpawu ezihlobene nokuntuleka kwe-estrogen. Lokhu kwenza kube isengezo esibalulekile enqolobaneni yokwelashwa etholakalayo yalesi simo, okunikeza ithemba elisha ezigulini nakubahlinzeki bezempilo ngokufanayo.
Ngaphandle kwendima yayo ekubhekaneni nokuntuleka kwe-estrogen, i-17α-Estradiol ibonise amandla ekuvimbeleni i-osteoporosis, isimo esibonakala ngokuncipha kwamathambo kanye nengozi eyengeziwe yokuphuka. Ngokukhuthaza impilo yamathambo nokuminyana, le nhlanganisela inamandla okunikeza indlela esheshayo yokulawula ukukhumuzeka kwamathambo, ikakhulukazi kwabesifazane abangemva kokuya esikhathini abasengozini enkulu yalesi simo. Ngamandla ayo okusekela amandla amathambo nobuqotho, i-17α-Estradiol imelela indlela ethembisayo yokukhuthaza impilo yesikhathi eside yamathambo.
Ngaphandle kwezicelo zayo empilweni yabesifazane, i-17α-Estradiol ibonise isithembiso ekubhekaneni ne-leukopenia ebangelwa i-chemotherapy noma i-radiotherapy yamathumba ayingozi. Lesi simo, esibonakala ngokuncipha kwenani lamangqamuzana amhlophe egazi, singashiya iziguli zisengozini yokungenwa izifo nezinye izinkinga. Ngokwandisa kakhulu inani lamangqamuzana amhlophe egazi, i-17α-Estradiol inikeza isisombululo esingaba khona sokulawula i-leukopenia nokusekela isimiso somzimba sokuzivikela ezifweni ngesikhathi sokwelashwa komdlavuza. Lokhu kumelela intuthuko enkulu ekunakekelweni okusekelayo okutholakalayo ezigulini ezinomdlavuza, okunikeza indlela entsha yokubhekana nalesi sici esiyinselele sokwelashwa komdlavuza.
Imithelela engaba khona ye-17α-Estradiol kumasu okushintsha ama-hormone ngesikhathi sokunqamuka kokuya esikhathini kanye nasekwelapheni izinkinga ze-neurodeergenerative ezifana nesifo i-Alzheimer's kanye ne-ischemic stroke iphawuleka ngokukhethekile. Nge-receptor yayo ekhethiwe, i-ER-X, kanye nendima yayo emisebenzini ye-autocrine/paracrine ebuchosheni obukhulayo nobudala, i-17α-Estradiol inesithembiso sokubhekana nezimo eziningi ezinomthelela omkhulu empilweni yeziguli. Njengoba ucwaningo kule ndawo luqhubeka nokuguquka, amandla okuthi i-17α-Estradiol inikeze izinketho ezintsha zokwelapha zalezi zimo eziyinselele kuyithemba elijabulisayo lekusasa lokunakekelwa kwezempilo.
Ekuphetheni, i-17α-Estradiol compound ibonise imiphumela ethembisayo ekwelapheni i-hypogonadism yabesifazane, i-osteoporosis, ne-leukopenia ebangelwa i-chemotherapy noma i-radiotherapy yamathumba amabi. Ngokuthinta okungaba khona kumasu okushintsha ama-hormone ekunqamukeni kokuya esikhathini kanye nokwelashwa kwezinkinga ze-neurodegenerative ezifana nesifo se-Alzheimer kanye ne-ischemic stroke, i-17α-Estradiol ikulungele ukwenza umthelela obalulekile emkhakheni wezempilo yabesifazane nangale kwalokho.
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