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I-MK-677 Inhlanganisela Eyingqayizivele Yokukhula Kwemisipha, Ukukhuthazela, Nokubuyiselwa
Incazelo Eningiliziwe
I-MK-677, eyaziwa nangokuthi i-Ibutamoren noma i-Nutrobal, iyinhlanganisela evame ukuhlotshaniswa ne-Selective Androgen Receptor Modulators (ama-SARM), nakuba kungeyona i-SARM ngokobuchwepheshe. Kuyi-hormone yokukhula yomlomo engeyona i-peptide ekhuthaza ukukhululwa kwe-hormone yokukhula ngama-receptors ahlukene ku-pituitary kanye ne-hypothalamus. I-MK-677 ilingisa isenzo se-ghrelin, i-hormone evuselela ukukhululwa kwe-hormone yokukhula. Lesi sihloko sihlola imiphumela nezinzuzo ze-MK-677, kufaka phakathi ukukhula kwemisipha, ukukhuthazela, ukutakula, ukushiswa kwamafutha, amandla, ukwanda kwamathambo, kanye nekhwalithi yokulala ethuthukisiwe.
Ukuzuza Kwemisipha:
I-MK-677 ikhuthaza ukukhululwa kwe-hormone yokukhula kanye ne-insulin-like growth factor 1 (IGF-1) ngaphandle kokuthinta amazinga e-cortisol. Le mpendulo ye-hormonal ithuthukisa ukwakheka kwamaprotheni emisipha yamathambo, okuholela ekukhuleni kwemisipha nokulondolozwa. Ikhono le-MK-677 lokuphakamisa amazinga e-IGF-1 kuze kufike emahoreni angu-24 ngemva komthamo kusiza ukugcina isimo se-anabolic, kube lula ukuzuza kwemisipha.
Ukubuyisela:
I-hormone yokukhula idlala indima ebalulekile ekukhuthazeni ukuphulukiswa kanye nokusheshisa ukululama ekulimaleni. I-MK-677 ikhuthaza ukukhululwa kwe-hormone yokukhula, okusheshisa ukulungiswa nokuvuselelwa kwezicubu zemisipha. Lokhu kuthola kabusha okusheshayo kuvumela abantu ukuthi baqale kabusha ukujima kwabo maduze, okuholela ekuthuthukeni nasekusebenzeni okuthuthukisiwe.
Ukushiswa kwamafutha:
I-hormone yokukhula iye yahlotshaniswa nokunciphisa ukugcinwa kwamafutha omzimba kanye nokuthuthukisa ukulahlekelwa kwamafutha ngesikhathi sokudla okukhawulelwe kwekhalori. Ikhono le-MK-677 lokukhuthaza ukukhululwa kwe-hormone yokukhula lingase libe nomthelela ekwandeni kwe-oxidation yamafutha kanye ne-metabolism ephumelelayo, esekela izinqubo zomzimba ezishisa amafutha.
Amandla:
Nakuba kungeyona inhlanganisela enamandla kakhulu yokuqinisa amandla, i-MK-677 isengakwazi ukunikeza ukwanda okulinganiselwe kwamandla. Abasebenzisi bavame ukuzwa ikhono lokuphakamisa izinsimbi ezisindayo futhi benze izivivinyo kalula kakhulu. Izinzuzo zamandla ezizuzwe nge-MK-677 zingaba nezinzuzo ezibalulekile zokuthuthukiswa kwemisipha jikelele nokusebenza ngokomzimba.
Ukuminyana Kwamathambo Okukhulisiwe:
Ucwaningo luye lwabonisa ukuthi i-MK-677 ingathuthukisa ukuminyana kwamaminerali amathambo kubantu. Ngokwandisa ukuminyana kwamathambo, i-MK-677 inciphisa ingozi yokuphuka futhi inikeza ukwesekwa okwengeziwe kwesakhiwo sohlaka olukhulayo lwemisipha. Amandla okuthuthukisa impilo yamathambo yindawo ebalulekile yocwaningo lwezicelo zezokwelapha ze-MK-677.
Ikhwalithi Yokulala Ethuthukisiwe:
Abasebenzisi be-MK-677 bavame ukubika ikhwalithi yokulala ethuthukisiwe, ngokuqala kokulala okusheshayo namaphethini okulala ajulile. Ukulala okunekhwalithi kubalulekile ukuze umuntu alulame futhi abe nempilo enhle. Ngokwenza lula ukulala okungcono, i-MK-677 ifaka isandla ekuthuthukisweni kwezinqubo zokutakula kanye namazinga wamandla engqondo nawomzimba anda.
I-MK-677, noma i-Ibutamoren, iyinhlanganisela eyingqayizivele ekhuthaza ukukhululwa kwe-hormone yokukhula ngokulingisa isenzo se-ghrelin. Inikeza uhla lwezinzuzo zabakhi bomzimba nabasubathi, okuhlanganisa ukukhula kwemisipha, ukukhuthazela, ukululama, ukushiswa kwamafutha, amandla anda, ukuminyana kwamathambo okuthuthukisiwe, kanye nekhwalithi yokulala ethuthukisiwe. Nakuba i-MK-677 ngokuvamile ibhekwa njengebekezelelwa kahle ngemiphumela emibi emincane, kubalulekile ukuyisebenzisa ngokuzibophezela futhi uthintane nochwepheshe bezempilo ngaphambi kokuqala noma yiluphi uhlobo lwemithi yokwengeza.
Ukucaciswa
