I-Paroxetine ivamise ukusetshenziswa njenge-hydrochloride noma i-methanesulfonate.I-Hydrochloride imhlophe noma imhlophe, i-crystalline powder e-deliquescent kalula, i-soluble kalula ku-methanol, inyibilika kancane ku-ethanol ne-methylene chloride, futhi incibilika kancane emanzini iyimpushana emhlophe ye-Methanel. ,akunaphunga,ukuncibilika emanzini>1g/ml,iphoyinti elincibilikayo 147~150℃.
I-Paroxetine imithi ebalulekile esetshenziselwa ukwelapha izimo ezihlukahlukene zempilo yengqondo, i-phenylpiperidine derivative kanye ne-SSRI engakwazi ukuvimbela ngokukhetha i-5-HT transporter, ivimbele ukuphindwa kabusha kwe-5-HT nge-presynaptic membrane, ikhulise futhi ikhulise umphumela. ye-5-HT, ngaleyo ndlela ikhiqize umphumela we-antidepressant. Umsebenzi wayo oyinhloko ukusebenza njenge-ejenti ye-antidepressant kanye ne-anxiolytic ngokuvimbela ngokukhetha ukuphinda kuthathwe i-serotonin ebuchosheni.I-Serotonin iyi-neurotransmitter edlala indima ebalulekile ekulawuleni isimo, imizwa, nokukhathazeka. Ngokuvimbela ukutholwa kabusha kwe-serotonin, i-Paroxetine isiza ekwandiseni amazinga e-serotonin ebuchosheni, ngaleyo ndlela ithuthukise isimo sengqondo futhi yehlise ukukhathazeka.
I-Paroxetine iphinde isetshenziswe ekwelapheni ezinye izimo zempilo yengqondo njenge-obsessive-compulsive disorder(OCD), ukuphazamiseka kokwesaba, ukuphazamiseka kokukhathazeka komphakathi, kanye ne-post-traumatic stress disorder (PTSD) .Indlela yokusebenza kwayo kulezi zimo ifana nayo Ngokwandisa amazinga e-serotonin ebuchosheni, i-Paroxetine isiza ekudambiseni izimpawu ezihlobene nalezi zinkinga.
Ukusetshenziswa kwe-Paroxetine kufaka phakathi izimo eziningi zempilo yengqondo, okuyenza ibe umuthi oguquguqukayo futhi obalulekile. Njenge-antidepressant, i-Paroxetine isetshenziselwa ukwehlisa izimpawu ze-depressive disorder, okuhlanganisa ukudabuka okungapheli, ukulahlekelwa isithakazelo emisebenzini evamile, izinguquko isifiso sokudla noma isisindo, ukuphazamiseka kokulala, nemizwa yokuzizwa ungelutho noma unomuzwa wecala.Ekwelapheni ukuphazamiseka kokukhathazeka, i-Paroxetine iyasebenza ekwehliseni izimpawu zokukhathazeka okujwayelekile, ukukhathazeka komphakathi kanye nokuphazamiseka kokwethuka.Isiza ekudambiseni ukukhathazeka ngokweqile, ukwesaba izimo zenhlalo. ,kanye nokuhlaselwa ukwethuka, okuvumela abantu ukuthi baphinde balawule imizwa yabo nokusebenza kwansuku zonke.
