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Zogulitsa Magulu
Zamgululi
Mapiritsi a Lenopril Amathandizira Kuwongolera Kuthamanga kwa Magazi ndi Thanzi Lamtima

Mapiritsi a Lenopril Amathandizira Kuwongolera Kuthamanga kwa Magazi ndi Thanzi Lamtima
Telmisartan Bwino antihypertensive Kuteteza aimpso

Telmisartan Bwino antihypertensive Kuteteza aimpso
Flumazenil A Selective GABAA Receptor Antagonist ndi Therapeutic Applications

Flumazenil A Selective GABAA Receptor Antagonist ndi Therapeutic Applications
Trametinib Kinase Inhibitor Kutsata BRAF V600 Mutation-Positive Cancers

Trametinib Kinase Inhibitor Kutsata BRAF V600 Mutation-Positive Cancers
Dabrafenib A Targeted Therapy for BRAF-Mutated Cancers

Dabrafenib A Targeted Therapy for BRAF-Mutated Cancers
Tirzepatide Dual GLP-1 ndi GIP Receptor Agonist for Weight Management and Glycemic Control

Tirzepatide Dual GLP-1 ndi GIP Receptor Agonist for Weight Management and Glycemic Control
Cisapride Gastric Stimulant for Indigestion and Digestive Disorders

Cisapride Gastric Stimulant for Indigestion and Digestive Disorders
YK-11 SARM Yamphamvu Yomanga Minofu, Kupeza Mphamvu, ndi Myostatin Inhibition

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Ostarine (MK-2866) SARM Yosiyanasiyana ya Kukula kwa Minofu, Kutaya Mafuta, ndi Kubwezeretsanso Thupi

Ostarine (MK-2866) SARM Yosiyanasiyana ya Kukula kwa Minofu, Kutaya Mafuta, ndi Kubwezeretsanso Thupi
MK-677 Wapadera Wophatikiza Kukula Kwa Minofu, Kupirira, ndi Kuchira

MK-677 Wapadera Wophatikiza Kukula Kwa Minofu, Kupirira, ndi Kuchira
0102030405
Dabrafenib A Targeted Therapy for BRAF-Mutated Cancers
Dabrafenib A Targeted Therapy for BRAF-Mutated Cancers
Dabrafenib A Targeted Therapy for BRAF-Mutated Cancers
Dabrafenib A Targeted Therapy for BRAF-Mutated Cancers

Dabrafenib A Targeted Therapy for BRAF-Mutated Cancers

Mtengo Wokonda: USD 50-60 / kg

  • Dzina lazogulitsa Dabrafenib
  • CAS No. 1195765-45-7
  • MF Mtengo wa C23H20F3N5O2S2
  • MW 519.561
  • Malingaliro a kampani EINECS 1592732-453-0
  • Kuchulukana 1.443
  • Malo otentha 653.726 °C pa 760 mmHg
Lumikizanani nafe
tsatanetsatane wazinthu

Kufotokozera Mwatsatanetsatane

Dabrafenib ndi choletsa pakamwa cha bioavailable cha mapuloteni a B-raf (BRAF) ndipo amagwiritsidwa ntchito ngati mankhwala oletsa khansa. Imasankha makhansa omwe amalumikizidwa ndi mtundu wosinthika wamtundu wa BRAF. Nkhaniyi ikufotokoza momwe dabrafenib imagwirira ntchito, zomwe zikuwonetsa, komanso kugwiritsa ntchito mankhwala a dabrafenib pochiza makhansa osiyanasiyana.

I. Kumvetsetsa Dabrafenib:
A. Inhibitor ya mapuloteni a B-raf (BRAF).
B. Kachitidwe kachitidwe: Kutsekereza chizindikiro cha mapuloteni osadziwika bwino ndikuwongolera kukula kwa maselo

17159473034104h3

II. Zizindikiro Zachipatala:

A. Monotherapy:

Osasinthika kapena metastatic melanoma yokhala ndi kusintha kwa BRAF V600E

B. Chithandizo chophatikiza ndi trametinib:

BRAF V600E-positive unresectable kapena metastatic melanoma

Khansara ya m'mapapo ya metastatic yopanda maselo yaying'ono

Metastatic anaplastic chithokomiro khansa

Zotupa zolimba zosasinthika kapena metastatic


III. Kachitidwe Kachitidwe:

A. Kusankha komanga ndi kuletsa kwa B-raf

B. Kuletsa kukula kwa maselo a chotupa ndi jini yosinthika ya BRAF


IV. Chithandizo cha Khansa ya Chithokomiro:

A. Mtundu wina wa khansa ya chithokomiro yomwe yafalikira ku minofu yapafupi kapena mbali zina za thupi

B. Kukana mankhwala am'mbuyomu


Kalasi ya V. Kinase Inhibitor:

A. Dabrafenib monga membala wa kinase inhibitors

B. Kuletsa zochita zomanga thupi zachilendo pofuna kupewa kuchulukana kwa maselo a khansa


Dabrafenib ndi mankhwala omwe amagwiritsidwa ntchito pochiza khansa ya BRAF-mutated. Monga inhibitor ya mapuloteni a B-raf (BRAF), imayang'ana ma cell a chotupa omwe ali ndi jini yosinthika ya BRAF, kuletsa kuchuluka kwawo. Dabrafenib amasonyezedwa chifukwa cha melanoma yosasinthika kapena metastatic, khansara ya m'mapapo yopanda maselo, khansara ya chithokomiro cha anaplastic, ndi zotupa zolimba zosasinthika kapena zolimba. Kuphatikiza mankhwala ndi trametinib kumawonjezera ntchito zake. Pomvetsetsa kusintha kwa majini m'maselo a khansa, mankhwala omwe amawathandizira monga dabrafenib amagwira ntchito yofunika kwambiri pakuwongolera zotsatira za chithandizo ndikuletsa kufalikira kwa maselo a khansa.

Kufotokozera

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